Table 1 |
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Correlation between P-Akt and HER-2 proteins in primary breast tumours |
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|
Negative (P-Akt 0,1) |
Positive (P-Akt 2,3) |
Total |
|
|
|
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|
Negative (HER2 0,1; counted/expected) |
111/100.2 |
130/140.8 |
241 |
|
Positive (HER2 2,3; counted/expected) |
32/42.8 |
71/60.2 |
103 |
|
Total |
143 |
201 |
344 |
|
|
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A total of 344 invasive ductal carcinomas were examined for expression of phospharylated Akt (P-Akt) and human epidermal growth factor receptor (HER)-2. A binary scoring system (0,1 versus 2,3) was used to compare staining between samples. Patients who overexpressed HER-2 were more likely to express P-Akt also. Statistical analysis was derived through the χ2 test (P < 0.01). |
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Kucab et al. Breast Cancer Research 2005 7:R796 doi:10.1186/bcr1294 |
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