Table 3 |
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|
Associations between selected risk factors for breast cancer andmammograms classified according to four methods |
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|
Characteristic |
Upper quartile |
High-risk patterns Reader NB |
||
|
|
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|
Reader GM ≥ 28.3% |
Reader GU ≥ 19.0% |
Wolfe |
Tabár |
|
|
|
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|
Age at screening |
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|
<60 years |
1.00 |
1.00 |
1.00 |
1.00 |
|
60–64 years |
0.65 |
0.74 |
0.64 |
0.79 |
|
65+ years |
0.52 |
0.53 |
0.59 |
0.64 |
|
P for trend |
<0.01 |
<0.01 |
<0.01 |
<0.03 |
|
Age at menarche |
||||
|
<13 years |
1.00 |
1.00 |
1.00 |
1.00 |
|
13–14 years |
1.24 |
1.28 |
1.26 |
1.36 |
|
14+ years |
0.90 |
1.04 |
0.81 |
0.76 |
|
P for trend |
0.99 |
0.50 |
0.67 |
0.70 |
|
Age at menopause |
||||
|
<48 years |
1.00 |
1.00 |
1.00 |
1.00 |
|
48–50 years |
0.80 |
0.85 |
0.90 |
0.87 |
|
51+ years |
0.95 |
1.14 |
1.38 |
1.11 |
|
P for trend |
0.83 |
0.47 |
0.06 |
0.61 |
|
Age at first birth |
||||
|
<20 years |
1.00 |
1.00 |
1.00 |
1.00 |
|
20–24 years |
0.99 |
1.15 |
1.41 |
1.14 |
|
25+ years |
1.30 |
1.66 |
1.67 |
1.40 |
|
P for trend |
0.27 |
0.07 |
0.05 |
0.15 |
|
Number of children |
||||
|
0 |
1.00 |
1.00 |
1.00 |
1.00 |
|
1 |
1.14 |
1.54 |
1.61 |
1.16 |
|
2 |
0.52 |
0.87 |
0.87 |
0.40 |
|
3 |
0.51 |
0.60 |
0.90 |
0.37 |
|
4+ |
0.18 |
0.23 |
0.41 |
0.21 |
|
P for trend – all |
<0.0001 |
<0.0001 |
<0.0001 |
<0.0001 |
|
Body mass index |
||||
|
<25 |
1.00 |
1.00 |
1.00 |
1.00 |
|
25–30 |
0.39 |
0.48 |
0.53 |
0.81 |
|
>30 |
0.15 |
0.19 |
0.24 |
0.36 |
|
P for trend |
<0.0001 |
<0.0001 |
<0.0001 |
<0.0001 |
|
|
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|
Multivariate odds ratios have been adjusted for age at screening, age at menarche, age at menopause, number of children, age at first birth, and body mass index where applicable. Total numbers in the multivariate models may vary slightly owing to missing values for covariates. |
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|
Gram et al. Breast Cancer Research 2005 7:R854 doi:10.1186/bcr1308 |
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