Table 2 |
||||||
|
Summary of the associations between clinicopathological parameters and EGFR overexpression and amplification |
||||||
|
Parameter |
EGFR IHC |
P |
EGFR CISH |
P |
||
|
|
|
|||||
|
Negative |
Overexpression |
No |
Amplified |
|||
|
|
||||||
|
Age (years) |
54.2 (13.3) |
48.8 (13.3) |
>0.05 |
50.4 (13.7) |
48.8 (12.7) |
>0.05 |
|
Size (cm) |
4.0 (3.2) |
4.4 (3.1) |
>0.05 |
3.8 (2.9) |
5.9 (3.9) |
>0.05 |
|
Lympho-vascular invasion |
||||||
|
No |
2 |
9 |
>0.05 |
9 |
2 |
>0.05 |
|
Yes |
2 |
9 |
7 |
4 |
||
|
Lymph node metastasis at diagnosis |
||||||
|
No |
3 |
11 |
>0.05 |
10 |
4 |
>0.05 |
|
Yes |
1 |
5 |
4 |
2 |
||
|
|
||||||
|
CISH, chromogenic in situ hybridization; EGFR, epidermal growth factor receptor. IHC, immunohistochemistry. |
||||||
|
Reis-Filho et al. Breast Cancer Research 2005 7:R1028 doi:10.1186/bcr1341 |
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