Figure 3.

Combined effect of rapamycin and CN-A on the growth of human cancer cells. (a) human breast cancer T-47D cells (3 × 10⁴ cells/ml) were treated with CN-A in the absence (black triangle) or the presence (black circle) of 0.5 ng/ml rapamycin for 5 days. (b) human breast cancer MBA-MB-231 (3 × 10⁴ cells/ml) cells were treated with CN-A in the absence (black triangle) or the presence (black circle) of 15 ng/ml rapamycin for 5 days. (c) human promyelocytic leukaemia NB-4 cells (3 × 10⁴ cells/ml) were treated with CN-A in the absence (black triangle) or the presence (black circle) of 0.5 ng/ml rapamycin for 5 days. Values are expressed as mean ± standard deviation for three separate experiments. CN-A, cotylenin A.