Table 2 |
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|
Upregulated genes in MCF-7 cells after exposure to rapamycin plus CN-A for 12 hours |
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| Gene expression ratio |
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|
|
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| GenBank number |
Gene name |
Rapamycin + CN-A |
Rapamycin |
CN-A |
|
|
||||
| NM_000358.1 |
Transforming growth factor-β-induced 68 kDa (TGFBI) |
8.16 |
1.74 |
5.2 |
| NM_001038.1 |
Sodium channel, nonvoltage-gated 1α(SCNN1A) |
6.99 |
1.49 |
4.26 |
| NM_002281.2 |
Keratin, hair, basic-1 (KRTHB1) |
6.96 |
1.27 |
12.8a |
| NM_001197.3 |
BCL2-interacting killer (apoptosis-inducing; BIK) |
6.76 |
2.37 |
3.59 |
| NM_004354.1 |
Cyclin G2 (CCNG2) |
6.08 |
3.07 |
3.22 |
| NM_005310.1 |
Growth factor receptor-bound protein 7 (GRB7) |
5.81 |
2.48 |
2.61 |
| NM_020898.1 |
KIAA1536 protein (KIAA1536) |
5.42 |
2.78 |
1.8 |
| NM_030777.2 |
Solute carrier family 2, member 10 (SLC2A10) |
5.09 |
1.53 |
2.51 |
| NM_005727.2 |
Tetraspan 1 (TSPAN-1) |
4.61 |
1.54 |
1.76 |
| NM_024709.1 |
Hypothetical protein FLJ14146 (FLJ14146) |
4.55 |
1.8 |
2.53 |
| NM_014376.1 |
Cytoplasmic FMR1 interacting protein 2 (CYFIP2) |
4.21 |
2.43 |
1.66 |
| NM_017644.1 |
Hypothetical protein FLJ20059 (FLJ20059) |
4.09 |
1.51 |
1.2 |
| NM_002166.1 |
Inhibitor of DNA binding 2 (ID2) |
4.03 |
1.23 |
2.93 |
| NM_006813.1 |
Proline rich 2 (PROL2) |
3.87 |
2.8 |
1.9 |
| NM_002885.1 |
RAP1, GTPase activating protein 1 (RAP1GA1) |
3.81 |
1.56 |
2.51 |
| NM_000755.2 |
Carnitine acetyltransferase (CRAT) |
3.79 |
1.75 |
2.45 |
| NM_031477.2 |
Hypothetical protein MGC10500 (MGC10500) |
3.72 |
2.18 |
2.29 |
| NM_012257.2 |
HMG-box containing protein 1 (HBP1) |
3.7 |
1.67 |
1.55 |
| NM_020169.2 |
Latexin protein (LXN) |
3.68 |
2.49 |
2.40 |
| NM_014417.2 |
BCL2 binding component 3 (BBC3) |
3.55 |
1.82 |
2.18 |
| NM_024642.2 |
GalNAc-T12 (GALNT12) |
3.49 |
1.49 |
2.53 |
| NM_016162.1 |
Inhibitor of growth family, member 4 (ING4) |
3.47 |
1.98 |
1.73 |
| NM_017673.2 |
Chromosome 1 open reading frame 26 (C1orf26) |
3.45 |
1.44 |
2.93 |
| NM_014353.2 |
RAB26, member RAS oncogene family (RAB26) |
3.42 |
2.40 |
1.49 |
| NM_005178.2 |
B-cell CLL/lymphoma 3 (BCL3) |
3.39 |
1.05 |
3.31 |
|
|
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|
aIncreased upper reliable levels. CN-A, cotylenin A. |
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|
Kasukabe et al. Breast Cancer Research 2005 7:R1097 doi:10.1186/bcr1344 |
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