Table 4 |
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|
Demographic, tumour and ductal lavage characteristics of women who developed breast cancer after study entry |
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| Subject |
|||||
|
|
|||||
| PMC13 |
PMC11 |
PMC14 |
PMC15 |
RMH08 |
|
|
|
|||||
| Age (years) |
53 |
51 |
41 |
48 |
37 |
| BRCA mutation |
A1 |
A1 |
A1 |
A1 |
A1 |
| Menopause status |
Post |
Post |
Pre |
Post |
Pre |
| Prior contralateral breast cancer (age in years) |
No |
Yes (42) |
Yes (35) |
Yes (38) |
Yes (34) |
| Previous mammogram (months) |
12 (normal) |
7 (normal) |
5 (normal) |
5 (normal) |
7 (normal) |
| Previous CBE (months) |
6 |
1 |
5 |
5 |
7 |
| 'Regular' BSEa |
Yes |
Yes |
Yes |
Yes |
Yes |
| Mode of detection |
Mammography |
Self |
Self |
Self |
Self |
| Distance from nipple (cm) |
5 |
3 |
Not recorded |
Not recorded |
2 |
| Histological characteristics |
Atypical medullary |
Lobular |
Ductal |
Ductal |
Ductal |
| Size (mm) |
5.2 |
20 |
10, 14, 10 (X3 separate foci) |
1.8 |
5 |
| Grade |
3 |
3 |
3 |
3 |
3 |
| ER status |
Negative |
Negative |
Negative |
Negative |
Negative |
| PR status |
Negative |
Negative |
Negative |
Negative |
Negative |
| Nodes |
Negative |
Negative |
Negative |
Negative |
Negative |
| Ductal lavage |
|||||
| Previous (months) |
5 |
1 |
5 |
12 |
4 |
| No. ducts cannulated/breast |
1 (X1occ) |
2 (X1occ) |
1 (X2occ) |
1 (X1occ) |
Unsuccessful |
| Cell count (duct)/ml |
6,666 |
2,500, 6,666 |
47,700 + 4,000 |
15,000 |
|
| Total cell count (duct) |
79,992 |
35,000, 93,324 |
525,555 + 40,000 |
180,000 |
|
| Cytology score |
Mild atypia |
Benign |
Benign |
No epithelial cells |
|
|
|
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|
a'Regular' as reported by subject (frequency not recorded). BSE, breast self examination; CBE, clinical breast examination; ER, oestrogen receptor; PR, progesterone receptor. |
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|
Mitchell et al. Breast Cancer Research 2005 7:R1122 doi:10.1186/bcr1348 |
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