Table 1

Effect of ovarian ablation in mice on MIN-O growth in fat pads

Mice

MIN-O size at 5 weeks after transplantation

Tumor latency

%FPF (no.)

Relative to control

P

TE₅₀ (weeks)

P

Control

67.50 ± 12.58 (4)

1

0.0001

6.60

0.0001

Ovariectomized

22.86 ± 7.56 (7)

0.34

10.10

%FPF, percentage of fat pad filled; MIN-O, mammary intraepithelial neoplasia outgrowth; TE₅₀, time for 50% of the transplanted mammary fat pads to produce palpable tumors.

Namba et al. Breast Cancer Research 2005 7:R881   doi:10.1186/bcr1317