Table 8 |
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|
Haplotype sharing in BRCA1/2 mutation negativea families |
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|
Family type |
BRCA1 haplotype sharedb |
BRCA2 haplotype sharedb |
BRCA1 and BRCA2 haplotype shared |
Neither BRCA1 nor BRCA2 shared |
Total |
|
|
|||||
|
Female breast cancer only |
13 |
10 |
10 |
46 |
79 |
|
Female breast and ovarian cancer |
11 |
3 |
0 |
15 |
29 |
|
Ovarian cancer only |
0 |
0 |
0 |
0 |
0 |
|
Female and male breast cancer |
1 |
2 |
1 |
3 |
7 |
|
Female and male breast cancer and ovarian cancer |
0 |
0 |
0 |
4 |
4 |
|
Male breast cancer only |
0 |
0 |
0 |
0 |
0 |
|
Total |
25 |
15 |
11 |
68 |
119 |
|
|
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|
aIndex cases screened by high-sensitivity methods. bAll cases from families on whom at least three blood samples were available from cases affected by breast or ovarian cancer share alleles at all markers tested. |
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|
Mann et al. Breast Cancer Research 2006 8:R12 doi:10.1186/bcr1377 |
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