Table 4 |
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|
Estimated cumulative risks of breast and ovarian cancer in BRCA1 and BRCA2 mutation carriers |
||||||
|
Age (years) |
BRCA1 |
BRCA2 |
||||
|
|
||||||
|
BC |
OC |
BC or OC |
BC |
OC |
BC or OC |
|
|
|
||||||
|
30 |
3 |
0 |
4 |
0.3 |
0 |
0.4 |
|
40 |
13 |
0 |
14 |
13 |
0.2 |
26 |
|
50 |
20 (0–45) |
1 (0–10) |
23 (0–48) |
21 (0–55) |
0.4 (0–2) |
35 (0–64) |
|
60 |
71 |
38 |
83 |
33 |
49 |
55 |
|
70 |
72 (0–93) |
38 (0–78) |
83 (34–96) |
75 (0–97) |
49 (0–81) |
89 (34–98) |
|
|
||||||
|
Shown are percentage cumulative risks (95% confidence interval). BC, breast cancer; OC, ovarian cancer. |
||||||
|
Antoniou et al. Breast Cancer Research 2006 8:R3 doi:10.1186/bcr1365 |
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