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Characteristics of women with breast cancer and their matched controls |
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| Variablea |
Cases of cancer (n = 252) |
Controls (n = 252) |
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|
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| Hypothesised risk factors |
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| Absolute breast volume FA (ml; median (IQR)) |
63.17 (88.54) |
52.99 (68.38) |
| Relative breast volume FA (%; median (IQR)) |
2.70 (3.63) |
2.49 (2.91) |
| Other potential risk factors/confounders |
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| BMI (n = 503; mean (SD)) |
23.8 (3.11) |
23.9 (3.22) |
| Height (cm; mean (SD)) |
161.7 (6.10) |
159.7 (5.88) |
| Age at menarche (years; n = 503; mean (SD)) |
13.0 (1.61) |
13.6 (1.68) |
| Age at 1st pregnancy (years; n = 400; mean (SD)) |
25.4 (4.19) |
23.9 (4.31) |
| Number of pregnancies (n = 503; median (IQR)) |
2 (2) |
2 (2) |
| Family history |
68 (27%) |
32 (13%) |
| Mean breast volume (ml; median (IQR)) |
569 (388) |
582 (370) |
| Parenchyma type: right breast |
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| N1 |
21 (8%) |
54 (21%) |
| P1 |
42 (17%) |
33 (13%) |
| P2 |
65 (26%) |
40 (16%) |
| DY |
124 (49%) |
125 (50%) |
| Parenchyma type: left breast |
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| N1 |
21 (8%) |
55 (22%) |
| P1 |
42 (17%) |
33 (13%) |
| P2 |
65 (26%) |
43 (17%) |
| DY |
124 (49%) |
121 (48%) |
| Menopausal status (n = 482) |
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| Pre |
99 (41%) |
76 (32%) |
| Peri |
44 (18%) |
49 (20%) |
| Post |
100 (41%) |
114 (48%) |
| Age at menopause (years; n = 212; median (IQR)) |
50 (4) |
47 (6) |
|
Values are numbers (percentages) unless stated otherwise. aIncomplete total is indicated in brackets where there are missing data. Absolute breast volume fluctuating asymmetry (FA) = unsigned values (|L - R|) of breast volume. Relative breast volume FA = 100 × |L - R| breast volume/[|L + R| breast volume] 0.5. BMI, body mass index; IQR, inter-quartile range; SD, standard deviation. | ||
Scutt et al. Breast Cancer Research 2006 8:R14 doi:10.1186/bcr1388 |
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