Table 4 |
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|
Cytoplasmic HER4: correlation with pathological variables and HER family |
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|
Test |
H4.77.16 histoscore |
HFR1 histoscore |
|||
|
|
|||||
|
P value |
Correlation |
P value |
Correlation |
||
|
|
|||||
|
NPI |
Kendall's tau-b |
0.004 |
Positive |
<0.001 |
Positive |
|
Size |
Kendall's tau-b |
<0.001 |
Positive |
0.021 |
Positive |
|
Grade |
Kendall's tau-b |
0.076 |
<0.001 |
Positive |
|
|
Nodal |
Kendall's tau-b |
0.004 |
Positive |
<0.001 |
Positive |
|
EGFR |
Mann-Whitney |
0.035 |
0.436 |
||
|
HER2 |
Mann-Whitney |
0.381 |
0.771 |
||
|
HER3 |
Mann-Whitney |
<0.001 |
Positive |
0.001 |
Positive |
|
|
|||||
|
Grade is the Bloom and Richardson grade. Nodal status is the number of positive nodes. NPI, Nottingham Prognostic Index (grade + nodal status + 0.02 × size in mm). EGFR, epidermal growth factor receptor. |
|||||
|
Tovey et al. Breast Cancer Research 2006 8:R19 doi:10.1186/bcr1394 |
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