Breast Cancer Research

official impact factor 5.79

Open Access Highly Access Research article

The effect of the stromal component of breast tumours on prediction of clinical outcome using gene expression microarray analysis

Susan J Cleator1,2*, Trevor J Powles3, Tim Dexter1, Laura Fulford1, Alan Mackay1, Ian E Smith4, Haukur Valgeirsson1, Alan Ashworth1 and Mitch Dowsett1,5

Author Affiliations

1 Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, SW3 6JB, London, UK

2 Current address: Department of Oncology, St. Mary's Hospital, Praed Street, London W2 1NY, UK

3 Parkside Hospital, Parkside, SW19 5NX, London, UK

4 Breast Unit, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK

5 Department of Academic Biochemistry, Royal Marsden Hospital, Fulham Road, SW3 6JJ, London, UK

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Breast Cancer Research 2006, 8:R32 doi:10.1186/bcr1506

Published: 21 June 2006

Additional files

Additional file 1:

A PDF file containing a dendrogram of flexible beta clustering with Spearman rank correlation on all core biopsy samples taken from 43 patients.

Format: PDF Size: 195KB Download file

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Additional file 3:

A word document containing a table that shows the characteristics of paired (repeat) core biopsy samples.

Format: DOC Size: 36KB Download file

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Additional file 4:

A word document containing a table that shows the oestrogen receptor (ER) predictive genes.

Format: DOC Size: 68KB Download file

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Additional file 5:

A word document containing a table that shows response prediction gene lists with expression ratios.

Format: DOC Size: 78KB Download file

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Additional file 6:

A PDF file showing Permutation to assess the generalisability of the reduction in error rate observed by addition of the 'histology gene'.

Format: PDF Size: 189KB Download file

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Additional file 2:

A word document containing the legend for additional data file 1.

Format: DOC Size: 19KB Download file

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Additional file 7:

A word document containing the legend for Additional data file 6.

Format: DOC Size: 20KB Download file

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