|
SAM (significance analysis of microarrays) analysis of genes correlated to percentage tumour content. |
|||||
| Gene name |
Genbank accession |
Unigene cluster ID |
Symbol |
Score (d) |
q-value (%) |
|
|
|||||
| ADP-ribosylation factor 1 |
AK023803 |
Hs.286221 |
ARF1 |
3.11 |
4.13 |
| CDC28 protein kinase regulatory subunit 2 |
BQ898943 |
Hs.83758 |
CKS2 |
2.73 |
4.13 |
| TRK-fused gene |
NM_006070 |
Hs.446568 |
TFG |
2.65 |
4.13 |
| Discs, large homolog 7 (Drosophila) |
NM_014750 |
Hs.77695 |
DLG7 |
2.60 |
4.13 |
| RAB6B, member RAS oncogene family |
NM_016577 |
Hs.352530 |
RAB6B |
2.59 |
4.13 |
| Epithelial cell transforming sequence 2 oncogene |
AY376439 |
Hs.293257 |
ECT2 |
2.56 |
4.13 |
| FXYD domain containing ion transport regulator 2 |
CR627143 |
Hs.413137 |
FXYD2 |
2.54 |
4.13 |
| Ubiquitin specific protease 9, X-linked (fat facets-like, Drosophila) |
NM_004652 |
Hs.77578 |
USP9X |
2.48 |
4.13 |
| Pitrilysin metalloproteinase 1 |
CR749279 |
Hs.528300 |
PITRM1 |
2.46 |
4.13 |
| Myeloid differentiation primary response gene (88) |
AK124685 |
Hs.82116 |
MYD88 |
2.44 |
4.13 |
| Baculoviral IAP repeat-containing 5 (survivin) |
NM_001012271 |
Hs.1578 |
BIRC5 |
2.42 |
4.13 |
| Polo-like kinase 4 (Drosophila) |
NM_014264 |
Hs.172052 |
PLK4 |
2.40 |
4.13 |
| 2',3'-cyclic nucleotide 3' phosphodiesterase |
NM_033133 |
Hs.443836 |
CNP |
2.40 |
4.13 |
| Triosephosphate isomerase 1 |
BM913099 |
Hs.83848 |
TPI1 |
2.39 |
4.13 |
| ALL1-fused gene from chromosome 1q |
BX649117 |
Hs.75823 |
AF1Q |
2.37 |
4.13 |
| Latent transforming growth factor beta binding protein 2 |
NM_000428 |
Hs.105689 |
LTBP2 |
-3.49 |
1.00 |
| LIM domain binding 2 |
AL832772 |
Hs.4980 |
LDB2 |
-3.43 |
1.00 |
| Collagen, type XV, alpha 1 |
NM_001855 |
Hs.409034 |
COL15A1 |
-3.39 |
1.00 |
| Cadherin 5, type 2, VE-cadherin (vascular epithelium) |
NM_001795 |
Hs.76206 |
CDH5 |
-3.39 |
1.00 |
| Forkhead box O1A (rhabdomyosarcoma) |
NM_002015 |
Hs.170133 |
FOXO1A |
-3.17 |
1.00 |
| TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous) |
BC035514 |
Hs.89640 |
TEK |
-3.02 |
1.00 |
| Regulator of G-protein signaling 5 |
NM_003617 |
Hs.24950 |
RGS5 |
-2.97 |
1.00 |
| Fasciculation and elongation protein zeta 1 (zygin I) |
NM_022549 |
Hs.79226 |
FEZ1 |
-2.90 |
1.00 |
| Vascular endothelial growth factor C |
NM_005429 |
Hs.79141 |
VEGFC |
-2.90 |
1.00 |
| Tumor necrosis factor receptor superfamily, member 10c, decoy without an intracellular domain |
NM_003841 |
Hs.253829 |
TNFRSF10C |
-2.82 |
1.00 |
| CDNA FLJ25106 fis, clone CBR01467 |
AK128814 |
Hs.432914 |
-2.79 |
1.00 |
|
| Alpha-2-macroglobulin |
CR749334 |
Hs.74561 |
A2M |
-2.77 |
1.00 |
| Meis1, myeloid ecotropic viral integration site 1 homolog 2 (mouse) |
NM_170677 |
Hs.362805 |
MEIS2 |
-2.71 |
1.00 |
| Tropomodulin 1 |
AK096156 |
Hs.404289 |
TMOD1 |
-2.70 |
1.00 |
| Isoleucine-tRNA synthetase |
NM_013417 |
Hs.172801 |
IARS |
-2.63 |
1.00 |
|
Positive values for score (bold) indicate positive correlation with percentage tumour, and negative values indicate inverse correlation with percentage tumour (underlined). The table has been truncated to show only genes with the lowest false discovery rates (q). | |||||
Cleator et al. Breast Cancer Research 2006 8:R32 doi:10.1186/bcr1506 |
|||||