Table 1

Mammary gland-specific promoters

Promoter

Origin

Expression

Activation

References


MMTV-LTR

Mouse mammary tumor virus

Breast epithelial cells, several other tissues

Steroid hormones

[42]

WAP

Whey acidic protein

Secretory mammary epithelium

Lactogenic hormones

[96,97]

C3(1)

Rat prostate steroid-binding protein (PSBP)

Epithelial cells of prostate and mammary gland

Estrogen (ductal and alveolar mammary epithelium)

[36]

B-LG

Bovine β-lactoglobulin

Mammary gland

Pregnancy and lactation

[98,99]

MT

Metallothionein

Most mammary cells

Zn2+

[100]


Fantozzi and Christofori Breast Cancer Research 2006 8:212   doi:10.1186/bcr1530