Table 4

Descriptive statistics by tumor subtypes in the Swedish cohort
Characteristic
 Basal-like
 ERBB2
 Luminal A
 Luminal B
 Normal-like
 p

n = 59
 n = 43
 n = 122
 n = 54
 n = 91
Cohort (n)




0.51e
     Stockholm
 25
 15
 39
 23
 37
     Uppsala
 34
 28
 83
 31
 54
Mean age at breast cancer diagnosis
 54
 59
 66
 61
 59
 <0.001e
Menopausal status (%)




0.0807e
     Premenopausal
 27.5
 13.3
 10.9
 24.4
 18.6
     Postmenopausal
 72.5
 86.7
 89.1
 75.6
 78.6
Mean tumor size (mm)
 22.9
 27.9
 21.8
 22.6
 20.7
 0.0345f
Tumor size < 21 mm (%)
 51
 35
 57
 42
 70
 <0.001e
Elston grade




<0.001e
     I
 3.5
 4.8
 34.5
 5.7
 43.2
     II
 21.1
 38.1
 54.3
 39.6
 52.3
     III
 75.4
 57.1
 11.2
 54.7
 4.5
p53 mutation (%)a
 64.7
 39.3
 9.6
 38.7
 3.7
 <0.001e
HRT (%)b




<0.001e
     Never
 60.0
 78.6
 81.6
 82.6
 48.6
     Former
 8.0
 7.1
 13.2
 8.7
 0.0
     Ongoing
 32.0
 14.3
 5.3
 8.7
 51.4
Lymph-positive (%)
 29
 48
 33
 41
 33
 0.312e
Estrogen receptor positive (%)
 45.8
 67.4
 97.5
 87.0
 92.3
 <0.001e
Progesterone receptor positive (%)
 54.2
 72.1
 93.2
 77.8
 92.3
 <0.001e
Genomically unstable (%)b
 76.0
 78.6
 56.4
 78.3
 37.1
 0.0031e
Genomic instability by ploidyb




0.0123e
     Diploid stable
 12.0
 7.1
 25.6
 4.3
 40.0
     Diploid unstable
 4.0
 0.0
 20.5
 26.1
 17.1
     Tetraploid stable
 4.0
 7.1
 7.7
 8.7
 8.6
     Tetraploid unstable
 16.0
 7.1
 12.8
 13.0
 0.0
     Aneuploid stable
 8.0
 7.1
 10.3
 8.7
 14.3
     Aneuploid unstable
 56.0
 71.4
 23.1
 39.1
 20.0
Treatment type (%)c




0.0353e
     None
 39.7
 35.7
 43.3
 35.8
 46.2
     Endocrine
 36.2
 45.2
 50.8
 56.6
 44.0
     Chemotherapy
 15.5
 16.7
 5.0
 5.7
 7.7
     Radiotherapy
 8.6
 2.4
 0.8
 1.9
 2.2
Breast cancer event within 5 years (%)d
 30
 51
 17
 43
 19
 <0.001e

ap53 data were available only for the Uppsala cohort. bHRT and genomic instability were available only for the Stockholm cohort. cFor the Stockholm cohort, endocrine comprises endocrine treatment alone and with any other combination. Chemotherapy refers to chemotherapy alone or associated with radiotherapy. Radiotherapy means radiotherapy alone. dBreast cancer event refers to relapse or death for breast cancer. ePearson χ2 test. fAnalysis of variance test.

Calza et al. Breast Cancer Research 2006 8:R34   doi:10.1186/bcr1517

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