Expression of selected subtype specific markers in the breast cancer dataset . (a) The y-axis shows the expression level of the gene, while the x-axis identifies each sample, ordered as in Figure 8. The vertical line shows the separation between sample clusters found in Figure 8. The right-most cluster shows decreased expression of estrogen receptor (ESR), HER2, and progesterone receptor (PGR) in most samples, and increased expression of keratin (KRT) 5 and gamma-glutamyl hydrolase (GGH). These markers are indicative of a mixture of basal-like and normal-like tumor subtypes. (b) Box plots showing the distributions of expression for subtype markers in the two observed clusters.
Finak et al. Breast Cancer Research 2006 8:R58 doi:10.1186/bcr1608