Table 2

Selected tissue markers identified for normal stroma and normal epithelium

Stromal expression

Epithelial expression

p value

Gene symbol

Gene name


24.41

1.00

1.02E-12

SFRP4

Secreted frizzled-related protein 4

18.44

1.00

1.02E-12

AOC3

Amine oxidase, copper containing 3 (vascular adhesion protein 1)

17.46

1.00

3.30E-11

PTGIS

Prostaglandin I2 synthase

17.11

1.00

7.97E-12

TEK

TEK tyrosine kinase, endothelial (venous malformations, multiple cutaneous and mucosal)

16.68

1.00

1.02E-12

IGFBP7

Insulin-like growth factor binding protein 7

15.65

1.00

1.02E-12

COL1A2

Collagen, type I, alpha 2

15.58

1.00

7.97E-12

WISP2

WNT1 inducible signaling pathway protein 2

14.37

1.00

1.94E-12

FBN1

Fibrillin 1

13.85

1.00

1.89E-11

CD36

CD36 antigen (collagen type I receptor, thrombospondin receptor)

1.00

2.37

8.32E-09

PPP1CB

Protein phosphatase 1, catalytic subunit, beta isoform

1.00

3.07

1.30E-08

K03200

Human melanoma-associated antigen p97

1.00

3.95

2.63E-09

PERP

TP53 apoptosis effector

1.00

4.08

7.50E-09

DDR1

Discoidin domain receptor family, member 1

1.00

4.75

2.11E-08

CDH1

Cadherin 1, type 1, E-cadherin (epithelial)

1.00

4.79

2.36E-07

KRT14

Keratin 14

1.00

5.14

1.60E-10

F11R

F11 receptor, junctional adhesion molecule 1

1.00

6.30

1.86E-07

KIT

v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog

1.00

6.35

5.97E-08

KRTCAP3

Keratinocyte associated protein 3.

1.00

9.07

2.92E-08

ELF5

E74-like factor 5 (epithelium-specific Ets transcription factor 2)


Finak et al. Breast Cancer Research 2006 8:R58   doi:10.1186/bcr1608

Open Data