Table 1

Progenitor cell properties (CD44+/CD24-) of various breast cancer cell lines
Cell line
 CD44+/CD24-
 CD44+/CD24+
 CD44-/CD24+
 CD44-/CD24-
 Tumor typea [24,50-52]
 Tissue sourceb [24,50-52]
 Cell type classification [25-27]
MDA-MB-231, TMD-231
 85 ± 5
 2
 0
 13 ± 5
 AC
 Pleural effusion
 Mesenchymal
TMD-436
 72 ± 5
 27 ± 5
 0
 7
 AC
 Pleural effusion
 Myoepithelial
Hs578T
 86 ± 5
 10 ± 5
 0
 2 ± 2
 CS
 Primary
 Mesenchymal
SUM1315
 97 ± 3
 0
 0
 3 ± 3
 IDAC
 Metastatic nodule
 Basal
HBL-100
 37 ± 5
 8
 2
 52 ± 6
 Immortal
 Milk
 Myoepithelial
MDA-MB-468
 3 ± 1
 90 ± 6
 7 ± 3
 0
 IAC
 Pleural effusion
 Basal
MCF-7
 0
 8 ± 3
 87 ± 2
 6 ± 2
 IDAC
 Pleural effusion
 Luminal
T47-D
 0
 0
 63 ± 3
 37 ± 2
 IDAC
 Pleural effusion
 Luminal
ZR-75-1
 0
 0
 64 ± 1
 36 ± 1
 IDAC
 Ascites
 Luminal
BT-474
 0
 0
 78 ± 7
 22 ± 7
 IDC
 Primary
 Luminal/ErbB2+
SK-BR-3
 0
 0
 84 ± 1
 16 ± 1
 AC
 Pleural effusion
 Luminal/ErbB2+
DU4475
 0
 0
 6 ± 1
 94 ± 1
 IDC
 Cutaneous nodule
 ND
MCF-10Aa
 17 ± 4
 5 ± 3
 20 ± 10
 58 ± 20
 Immortal
 Fibrocyst
 Basal

aPercentage of MCF10A cell progenitor and other subpopulation was influenced by species and batch of serum in culture media. AC, adenocarcinoma; CS, carcinosarcoma; IDAC, infiltrating ductal adenocarcinoma; IAC, Invasive adenocarcinoma; IDC, Invasive ductal carcinoma; ND, not determined.

Sheridan et al. Breast Cancer Research 2006 8:R59   doi:10.1186/bcr1610

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