Table 1

Progenitor cell properties (CD44+/CD24-) of various breast cancer cell lines

Cell line

CD44+/CD24-

CD44+/CD24+

CD44-/CD24+

CD44-/CD24-

Tumor typea [24,50-52]

Tissue sourceb [24,50-52]

Cell type classification [25-27]


MDA-MB-231, TMD-231

85 ± 5

2

0

13 ± 5

AC

Pleural effusion

Mesenchymal

TMD-436

72 ± 5

27 ± 5

0

7

AC

Pleural effusion

Myoepithelial

Hs578T

86 ± 5

10 ± 5

0

2 ± 2

CS

Primary

Mesenchymal

SUM1315

97 ± 3

0

0

3 ± 3

IDAC

Metastatic nodule

Basal

HBL-100

37 ± 5

8

2

52 ± 6

Immortal

Milk

Myoepithelial

MDA-MB-468

3 ± 1

90 ± 6

7 ± 3

0

IAC

Pleural effusion

Basal

MCF-7

0

8 ± 3

87 ± 2

6 ± 2

IDAC

Pleural effusion

Luminal

T47-D

0

0

63 ± 3

37 ± 2

IDAC

Pleural effusion

Luminal

ZR-75-1

0

0

64 ± 1

36 ± 1

IDAC

Ascites

Luminal

BT-474

0

0

78 ± 7

22 ± 7

IDC

Primary

Luminal/ErbB2+

SK-BR-3

0

0

84 ± 1

16 ± 1

AC

Pleural effusion

Luminal/ErbB2+

DU4475

0

0

6 ± 1

94 ± 1

IDC

Cutaneous nodule

ND

MCF-10Aa

17 ± 4

5 ± 3

20 ± 10

58 ± 20

Immortal

Fibrocyst

Basal


aPercentage of MCF10A cell progenitor and other subpopulation was influenced by species and batch of serum in culture media. AC, adenocarcinoma; CS, carcinosarcoma; IDAC, infiltrating ductal adenocarcinoma; IAC, Invasive adenocarcinoma; IDC, Invasive ductal carcinoma; ND, not determined.

Sheridan et al. Breast Cancer Research 2006 8:R59   doi:10.1186/bcr1610

Open Data