|
List of 43 genes able to discriminate between well- and poorly differentiated DCIS |
||||
| Rank |
NKI ID |
Symbol |
Annotation |
Accession no. |
|
|
||||
| 1 |
108691 |
ACK1 |
Activated p21cdc42Hs kinase |
AA427891 |
| 2 |
109246 |
BCL2 |
B-cell CLL/lymphoma 2 |
W63749 |
| 3 |
109268 |
ALDH3A2 |
Aldehyde dehydrogenase 3 family, member A2 |
AA633569 |
| 4 |
109236 |
BTD |
Biotinidase |
R17765 |
| 5 |
108595 |
CCL19 |
Small inducible cytokine subfamily A (Cys-Cys), member 19 |
AA680186 |
| 6 |
100524 |
CELSR2 |
Cadherin, EGF LAG seven-pass G-type receptor 2, flamingo (Drosophila) homolog |
H39187 |
| 7 |
126868 |
TMC4 |
DKFZP586J0619 protein |
AA991211 |
| 8 |
100708 |
SLC39A6 |
LIV-1 protein, oestrogen regulated |
H29315 |
| 9 |
109170 |
C4A |
Complement component 4A |
AA664406 |
| 10 |
109127 |
ESR1 |
Oestrogen receptor 1 |
AA291749 |
| 11 |
128702 |
EST |
AI313031 |
|
| 12 |
121012 |
HSHIN1 |
Hin-1 |
AA902831 |
| 13 |
128095 |
PCSK6 |
Paired basic amino acid cleaving system 4 |
W85807 |
| 14 |
128052 |
ARHGEF7 |
PAK-interacting exchange factor beta |
AA452871 |
| 15 |
128493 |
GMFG |
Glia maturation factor, gamma |
AI311932 |
| 16 |
123382 |
HIG1 |
Likely ortholog of mouse hypoxia induced gene 1 |
T74105 |
| 17 |
129689 |
C1orf21 |
Chromosome 1 open reading frame 21 |
AA406569 |
| 18 |
102289 |
ETFA |
Electron-transfer-flavoprotein, alpha polypeptide (glutaric aciduria II) |
T57919 |
| 19 |
126124 |
FLJ20152 |
Hypothetical protein |
AA918685 |
| 20 |
127815 |
PLAT |
Plasminogen activator, tissue |
R38933 |
| 21 |
101559 |
NPY1R |
Neuropeptide Y receptor Y1 |
R43817 |
| 22 |
100260 |
MAL |
Mal, T-cell differentiation protein |
AA227885 |
| 23 |
127969 |
CRYAA |
Crystallin, alpha A |
H84722 |
| 24 |
128244 |
SERPINA3 |
Serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 |
AA704242 |
| 25 |
108649 |
Human clone 23948 mRNA sequence |
H15114 |
|
| 26 |
106399 |
GRTP1 |
Hypothetical protein FLJ22474 |
N52651 |
| 27 |
123478 |
FLJ14712 |
Hypothetical protein FLJ14712 |
N79050 |
| 28 |
117207 |
EMP3 |
Epithelial membrane protein 3 |
W73810 |
| 29 |
111787 |
ZNF451 |
H. sapiens cDNA FLJ13010 fis, clone NT2RP3000542 |
AA486412 |
| 30 |
109502 |
KITLG |
H. sapiens cDNA: FLJ21592 fis, clone COL07036 |
H11088 |
| 31 |
109315 |
UCP2 |
Uncoupling protein 2 (mitochondrial, proton carrier) |
H61243 |
| 32 |
118532 |
NUPL1 |
PRO2463 protein |
AA772502 |
| 33 |
100263 |
MYB |
V-myb avian myeloblastosis viral oncogene homolog |
N49284 |
| 34 |
128249 |
CD3E |
CD3E antigen, epsilon polypeptide (TiT3 complex) |
AA933862 |
| 35 |
131226 |
IL7R |
Interleukin 7 receptor |
T65739 |
| 36 |
100104 |
SELL |
Selectin L (lymphocyte adhesion molecule 1) |
H00662 |
| 37 |
108671 |
BCAT2 |
Branched chain aminotransferase 2, mitochondrial |
AA436410 |
| 38 |
116984 |
ATP5B |
ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide |
AA708298 |
| 39 |
108376 |
LAMA3 |
Laminin, alpha 3 (nicein [150 kD], kalinin [165 kD], BM600 [150 kD], epilegrin) |
AA001432 |
| 40 |
104944 |
SLC7A2 |
Solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 |
R26163 |
| 41 |
100840 |
THOC1 |
Nuclear matrix protein p84 |
AA129297 |
| 42 |
100650 |
SHFM1 |
Deleted in split-hand/split-foot 1 region |
H85464 |
| 43 |
101429 |
SIAT1 |
Sialyltransferase 1 (beta-galactoside alpha-2,6-sialytransferase) |
AA598652 |
|
DCIS, ductal carcinoma in situ; EST, expressed sequence tag; NKI ID, Netherlands Cancer Institute (Amsterdam, The Netherlands) identification number. | ||||
Hannemann et al. Breast Cancer Research 2006 8:R61 doi:10.1186/bcr1613 |
||||