Table 2

Analysis of the concentration of EBV in matched blood and tumor specimens

Category
Peripheral blood-/tumor-
Peripheral blood+/tumor+
Peripheral blood+/tumor-
Peripheral blood-/tumor+

Number (percentage of total)a
10 (42)
7 (29)
3 (12)
4 (17)
Ratio of EBV genomesb in blood versus tumor (range of EBV levels in peripheral blood)
0.0
5.0 (0.6–22.0)
Undefined
Undefined
Range of EBV levelsc in peripheral blood
0.0
8.0 (2.0–22.0)
4 (1.0–8.0)
0.0
Range of EBV levelsc in tumor specimens
0.0
5.0 (1–14)
0.0
1.0 (1.0–2.0)

aN = 24. bThe number of Epstein-Barr virus (EBV) genomes was determined in 160,000 cell equivalents of DNA isolated from peripheral blood and tumor specimens. cRange (highest level to lowest level of EBV genomes in the peripheral blood).

Perkins et al. Breast Cancer Research 2006 8:R70   doi:10.1186/bcr1627