Table 1 |
|||||
|
Summary characteristics for affected and unaffected carriers |
|||||
| Parameter |
Total |
Affected |
Unaffected |
||
| BRCA1 |
BRCA2 |
BRCA1 |
BRCA2 |
||
|
|
|||||
| Number of carriers, n |
789 |
248 |
209 |
218 |
114 |
| Age at censoring, years (mean ± SD) |
45.0 ± 11.3 |
42.9 ± 9.6 |
43.9 ± 9.3 |
46.8 ± 13.0 |
48.3 ± 13.0 |
| Year of birth, n (%) |
|||||
| Before 1940 |
247 |
78 (31.5) |
64 (30.6) |
78 (35.8) |
27 (23.7) |
| 1940 to 1949 |
185 |
69 (27.8) |
61 (29.2) |
40 (18.3) |
15 (13.2) |
| 1950 to 1959 |
169 |
58 (23.4) |
48 (23.0) |
34 (15.6) |
29 (25.4) |
| 1960 and after |
188 |
43 (17.3) |
36 (17.2) |
66 (30.3) |
43 (37.7) |
| Censoring age, n (%) |
|||||
| <55 years |
670 |
226 (91.1) |
185 (88.5) |
172 (78.9) |
87 (76.3) |
| ≥55 years |
119 |
22 (8.9) |
24 (11.5) |
46 (21.1) |
27 (23.7) |
| Oophorectomy before censoring age, n |
45 |
5 |
7 |
25 |
8 |
|
|
|||||
|
Antoniou et al. Breast Cancer Research 2006 8:R72 doi:10.1186/bcr1630 |
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