Breast Cancer Research | Volume 9 Issue 1

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	Volume 9 Issue 1
	Comment
	Editorial The continuing search for cancer-causing somatic mutations Gillian L Dalgliesh, P Andrew Futreal Breast Cancer Research 2007, 9:101 (22 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Viewpoint Obesity hormone leptin: a new target in breast cancer? Eva Surmacz Breast Cancer Research 2007, 9:301 (26 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review
	Review Lipid peroxidation, oxidative stress genes and dietary factors in breast cancer protection: a hypothesis Manuela Gago-Dominguez, Xuejuan Jiang, J Esteban Castelao Breast Cancer Research 2006, 9:201 (10 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review HER2 therapy. HER2 (ERBB2): functional diversity from structurally conserved building blocks Ralf Landgraf Breast Cancer Research 2007, 9:202 (22 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Involvement of α₆β₄integrin in the mechanisms that regulate breast cancer progression Giulia Bon, Valentina Folgiero, Selene Di Carlo, Ada Sacchi, Rita Falcioni Breast Cancer Research 2007, 9:203 (23 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis! Steven M Anderson, Michael C Rudolph, James L McManaman, Margaret C Neville Breast Cancer Research 2007, 9:204 (28 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research
	Research article SirT1 modulates the estrogen–insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice Hongzhe Li, Grace K Rajendran, Ninning Liu, Carol Ware, Brian P Rubin, Yansong Gu Breast Cancer Research 2007, 9:R1 (3 January 2007) Abstract \| Full text \| PDF \| PubMed
	Research article IGFBP3 mRNA expression in benign and malignant breast tumors Zefang Ren, Aesun Shin, Qiuyin Cai, Xiao-Ou Shu, Yu-Tang Gao, Wei Zheng Breast Cancer Research 2007, 9:R2 (8 January 2007) Abstract \| Full text \| PDF \| PubMed
	Research article A polymorphism in the 3' untranslated region of the gene encoding prostaglandin endoperoxide synthase 2 is not associated with an increase in breast cancer risk: a nested case-control study David G Cox, Julie Buring, Susan E Hankinson, David J Hunter Breast Cancer Research 2007, 9:R3 (10 January 2007) Abstract \| Full text \| PDF \| PubMed
	Research article Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival Laura G Fulford, Jorge S Reis-Filho, Ken Ryder, Chris Jones, Cheryl E Gillett, Andrew Hanby, Douglas Easton, Sunil R Lakhani Breast Cancer Research 2007, 9:R4 (11 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Basal-like tumours have a distinct pattern of metastatic spread; they appear to have good long-term survival relative to other grade 3 tumours, but survival following metastases is poor.
	Research article Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas Stephen J Chanock, Laurie Burdett, Meredith Yeager, Victor Llaca, Anita Langerød, Shafaq Presswalla, Rolf Kaaresen, Robert L Strausberg, Daniela S Gerhard, Vessela Kristensen, Charles M Perou, Anne-Lise Børresen-Dale Breast Cancer Research 2007, 9:R5 (16 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Characterising somatic sequence alterations based on expression profiling analysis is important for the discovery of cancer genes, a study of 21 genes selected in breast carcinomas has shown.
	Research article Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients Lisa K Dunnwald, Mary Rossing, Christopher I Li Breast Cancer Research 2007, 9:R6 (19 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer Pia Wegman, Sauli Elingarami, John Carstensen, Olle Stål, Bo Nordenskjöld, Sten Wingren Breast Cancer Research 2007, 9:R7 (23 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article An expression signature of syndecan-1 (CD138), E-cadherin and c-met is associated with factors of angiogenesis and lymphangiogenesis in ductal breast carcinoma in situ Martin Götte, Christian Kersting, Isabel Radke, Ludwig Kiesel, Pia Wülfing Breast Cancer Research 2007, 9:R8 (23 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Vitamin D pathway gene polymorphisms, diet, and risk of postmenopausal breast cancer: a nested case-control study Marjorie L McCullough, Victoria L Stevens, William R Diver, Heather S Feigelson, Carmen Rodriguez, Robin M Bostick, Michael J Thun, Eugenia E Calle Breast Cancer Research 2007, 9:R9 (23 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Risk of second primary cancer in men with breast cancer Sacha Satram-Hoang, Argyrios Ziogas, Hoda Anton-Culver Breast Cancer Research 2007, 9:R10 (25 January 2007) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Men diagnosed with a first primary breast cancer have a 16% increased risk of developing a second cancer compared with the general male population, a study of nearly 2,000 patients has shown.
	Research article Diet and body constitution in relation to subgroups of breast cancer defined by tumour grade, proliferation and key cell cycle regulators Signe Borgquist, Elisabet Wirfält, Karin Jirström, Lola Anagnostaki, Bo Gullberg, Göran Berglund, Jonas Manjer, Göran Landberg Breast Cancer Research 2007, 9:R11 (25 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models Lakshmanaswamy Rajkumar, Frances S Kittrell, Raphael C Guzman, Powel H Brown, Satyabrata Nandi, Daniel Medina Breast Cancer Research 2007, 9:R12 (26 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Research article Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells Mina Yaar, Mark S Eller, Izabela Panova, John Kubera, Lee Wee, Kenneth H Cowan, Barbara A Gilchrest Breast Cancer Research 2007, 9:R13 (26 January 2007) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells, providing an insight into innate cancer avoidance mechanisms that may lead to a novel approach to treating breast cancer.
	Research article Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity Gillian E Stillfried, Darren N Saunders, Marie Ranson Breast Cancer Research 2007, 9:R14 (28 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Oestrogen receptor negative breast cancers exhibit high cytokine content Carine Chavey, Frédéric Bibeau, Sophie Gourgou-Bourgade, Sandrine Burlinchon, Florence Boissière, Daniel Laune, Sylvie Roques, Gwendal Lazennec Breast Cancer Research 2007, 9:R15 (29 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Basal-like phenotype is not associated with patient survival in estrogen-receptor-negative breast cancers Mervi Jumppanen, Sofia Gruvberger-Saal, Päivikki Kauraniemi, Minna Tanner, Pär-Ola Bendahl, Mikael Lundin, Morten Krogh, Pasi Kataja, Åke Borg, Mårten Fernö, Jorma Isola Breast Cancer Research 2007, 9:R16 (31 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family Meng-Lay Lin, Jae-Hyun Park, Toshihiko Nishidate, Yusuke Nakamura, Toyomasa Katagiri Breast Cancer Research 2007, 9:R17 (6 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study Rulla M Tamimi, David G Cox, Peter Kraft, Michael N Pollak, Christopher A Haiman, Iona Cheng, Matthew L Freedman, Susan E Hankinson, David J Hunter, Graham A Colditz Breast Cancer Research 2007, 9:R18 (14 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Common genetic variation in insulin-like growth factor (IGF)-1 is strongly associated with percent mammographic density, a strong risk factor for breast cancer, a large case-control study has shown.
	Research article Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors Stephanie C Lebret, Donald F Newgreen, Erik W Thompson, M Leigh Ackland Breast Cancer Research 2007, 9:R19 (20 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Gene promoter hypermethylation in ductal lavage fluid from healthy BRCA gene mutation carriers and mutation-negative controls Imogen Locke, Zsofia Kote-Jarai, Mary Jo Fackler, Elizabeth Bancroft, Peter Osin, Ashutosh Nerurkar, Louise Izatt, Gabriella Pichert, Gerald PH Gui, Rosalind A Eeles Breast Cancer Research 2007, 9:R20 (26 February 2007) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Analysis of free DNA from ductal lavage fluid showed increased levels of aberrant methylation in BRCA mutation carriers, and may be a useful alternative marker for breast cancer risk.

	Volume 9 Issue 1
	Comment
	Editorial The continuing search for cancer-causing somatic mutations Gillian L Dalgliesh, P Andrew Futreal Breast Cancer Research 2007, 9:101 (22 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Viewpoint Obesity hormone leptin: a new target in breast cancer? Eva Surmacz Breast Cancer Research 2007, 9:301 (26 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review
	Review Lipid peroxidation, oxidative stress genes and dietary factors in breast cancer protection: a hypothesis Manuela Gago-Dominguez, Xuejuan Jiang, J Esteban Castelao Breast Cancer Research 2006, 9:201 (10 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review HER2 therapy. HER2 (ERBB2): functional diversity from structurally conserved building blocks Ralf Landgraf Breast Cancer Research 2007, 9:202 (22 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Involvement of α₆β₄integrin in the mechanisms that regulate breast cancer progression Giulia Bon, Valentina Folgiero, Selene Di Carlo, Ada Sacchi, Rita Falcioni Breast Cancer Research 2007, 9:203 (23 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Key stages in mammary gland development. Secretory activation in the mammary gland: it's not just about milk protein synthesis! Steven M Anderson, Michael C Rudolph, James L McManaman, Margaret C Neville Breast Cancer Research 2007, 9:204 (28 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research
	Research article SirT1 modulates the estrogen–insulin-like growth factor-1 signaling for postnatal development of mammary gland in mice Hongzhe Li, Grace K Rajendran, Ninning Liu, Carol Ware, Brian P Rubin, Yansong Gu Breast Cancer Research 2007, 9:R1 (3 January 2007) Abstract \| Full text \| PDF \| PubMed
	Research article IGFBP3 mRNA expression in benign and malignant breast tumors Zefang Ren, Aesun Shin, Qiuyin Cai, Xiao-Ou Shu, Yu-Tang Gao, Wei Zheng Breast Cancer Research 2007, 9:R2 (8 January 2007) Abstract \| Full text \| PDF \| PubMed
	Research article A polymorphism in the 3' untranslated region of the gene encoding prostaglandin endoperoxide synthase 2 is not associated with an increase in breast cancer risk: a nested case-control study David G Cox, Julie Buring, Susan E Hankinson, David J Hunter Breast Cancer Research 2007, 9:R3 (10 January 2007) Abstract \| Full text \| PDF \| PubMed
	Research article Basal-like grade III invasive ductal carcinoma of the breast: patterns of metastasis and long-term survival Laura G Fulford, Jorge S Reis-Filho, Ken Ryder, Chris Jones, Cheryl E Gillett, Andrew Hanby, Douglas Easton, Sunil R Lakhani Breast Cancer Research 2007, 9:R4 (11 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Basal-like tumours have a distinct pattern of metastatic spread; they appear to have good long-term survival relative to other grade 3 tumours, but survival following metastases is poor.
	Research article Somatic sequence alterations in twenty-one genes selected by expression profile analysis of breast carcinomas Stephen J Chanock, Laurie Burdett, Meredith Yeager, Victor Llaca, Anita Langerød, Shafaq Presswalla, Rolf Kaaresen, Robert L Strausberg, Daniela S Gerhard, Vessela Kristensen, Charles M Perou, Anne-Lise Børresen-Dale Breast Cancer Research 2007, 9:R5 (16 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Characterising somatic sequence alterations based on expression profiling analysis is important for the discovery of cancer genes, a study of 21 genes selected in breast carcinomas has shown.
	Research article Hormone receptor status, tumor characteristics, and prognosis: a prospective cohort of breast cancer patients Lisa K Dunnwald, Mary Rossing, Christopher I Li Breast Cancer Research 2007, 9:R6 (19 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Genetic variants of CYP3A5, CYP2D6, SULT1A1, UGT2B15 and tamoxifen response in postmenopausal patients with breast cancer Pia Wegman, Sauli Elingarami, John Carstensen, Olle Stål, Bo Nordenskjöld, Sten Wingren Breast Cancer Research 2007, 9:R7 (23 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article An expression signature of syndecan-1 (CD138), E-cadherin and c-met is associated with factors of angiogenesis and lymphangiogenesis in ductal breast carcinoma in situ Martin Götte, Christian Kersting, Isabel Radke, Ludwig Kiesel, Pia Wülfing Breast Cancer Research 2007, 9:R8 (23 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Vitamin D pathway gene polymorphisms, diet, and risk of postmenopausal breast cancer: a nested case-control study Marjorie L McCullough, Victoria L Stevens, William R Diver, Heather S Feigelson, Carmen Rodriguez, Robin M Bostick, Michael J Thun, Eugenia E Calle Breast Cancer Research 2007, 9:R9 (23 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Risk of second primary cancer in men with breast cancer Sacha Satram-Hoang, Argyrios Ziogas, Hoda Anton-Culver Breast Cancer Research 2007, 9:R10 (25 January 2007) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Men diagnosed with a first primary breast cancer have a 16% increased risk of developing a second cancer compared with the general male population, a study of nearly 2,000 patients has shown.
	Research article Diet and body constitution in relation to subgroups of breast cancer defined by tumour grade, proliferation and key cell cycle regulators Signe Borgquist, Elisabet Wirfält, Karin Jirström, Lola Anagnostaki, Bo Gullberg, Göran Berglund, Jonas Manjer, Göran Landberg Breast Cancer Research 2007, 9:R11 (25 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Hormone-induced protection of mammary tumorigenesis in genetically engineered mouse models Lakshmanaswamy Rajkumar, Frances S Kittrell, Raphael C Guzman, Powel H Brown, Satyabrata Nandi, Daniel Medina Breast Cancer Research 2007, 9:R12 (26 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| F1000 Biology
	Research article Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells Mina Yaar, Mark S Eller, Izabela Panova, John Kubera, Lee Wee, Kenneth H Cowan, Barbara A Gilchrest Breast Cancer Research 2007, 9:R13 (26 January 2007) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Telomeric DNA induces apoptosis and senescence of human breast carcinoma cells, providing an insight into innate cancer avoidance mechanisms that may lead to a novel approach to treating breast cancer.
	Research article Plasminogen binding and activation at the breast cancer cell surface: the integral role of urokinase activity Gillian E Stillfried, Darren N Saunders, Marie Ranson Breast Cancer Research 2007, 9:R14 (28 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Oestrogen receptor negative breast cancers exhibit high cytokine content Carine Chavey, Frédéric Bibeau, Sophie Gourgou-Bourgade, Sandrine Burlinchon, Florence Boissière, Daniel Laune, Sylvie Roques, Gwendal Lazennec Breast Cancer Research 2007, 9:R15 (29 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Basal-like phenotype is not associated with patient survival in estrogen-receptor-negative breast cancers Mervi Jumppanen, Sofia Gruvberger-Saal, Päivikki Kauraniemi, Minna Tanner, Pär-Ola Bendahl, Mikael Lundin, Morten Krogh, Pasi Kataja, Åke Borg, Mårten Fernö, Jorma Isola Breast Cancer Research 2007, 9:R16 (31 January 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Involvement of maternal embryonic leucine zipper kinase (MELK) in mammary carcinogenesis through interaction with Bcl-G, a pro-apoptotic member of the Bcl-2 family Meng-Lay Lin, Jae-Hyun Park, Toshihiko Nishidate, Yusuke Nakamura, Toyomasa Katagiri Breast Cancer Research 2007, 9:R17 (6 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Common genetic variation in IGF1, IGFBP-1, and IGFBP-3 in relation to mammographic density: a cross-sectional study Rulla M Tamimi, David G Cox, Peter Kraft, Michael N Pollak, Christopher A Haiman, Iona Cheng, Matthew L Freedman, Susan E Hankinson, David J Hunter, Graham A Colditz Breast Cancer Research 2007, 9:R18 (14 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Common genetic variation in insulin-like growth factor (IGF)-1 is strongly associated with percent mammographic density, a strong risk factor for breast cancer, a large case-control study has shown.
	Research article Induction of epithelial to mesenchymal transition in PMC42-LA human breast carcinoma cells by carcinoma-associated fibroblast secreted factors Stephanie C Lebret, Donald F Newgreen, Erik W Thompson, M Leigh Ackland Breast Cancer Research 2007, 9:R19 (20 February 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Gene promoter hypermethylation in ductal lavage fluid from healthy BRCA gene mutation carriers and mutation-negative controls Imogen Locke, Zsofia Kote-Jarai, Mary Jo Fackler, Elizabeth Bancroft, Peter Osin, Ashutosh Nerurkar, Louise Izatt, Gabriella Pichert, Gerald PH Gui, Rosalind A Eeles Breast Cancer Research 2007, 9:R20 (26 February 2007) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Analysis of free DNA from ductal lavage fluid showed increased levels of aberrant methylation in BRCA mutation carriers, and may be a useful alternative marker for breast cancer risk.

Explore journal

Articles

Volume 9 Issue 1

Comment

Review

Research