Table 2

Risk of second primary cancer among men with first primary breast cancer

Cancer site
N
PERYR
OBS
EXP
SIR (95 percent CI)

All malignancies, breast included
1,926
8,460.08
221
190.42
1.16 (1.01–1.32)
All malignancies, breast excluded
1,926
8,529.63
201
191.63
1.05 (0.91–1.20)
Prostate
1,926
8,803.74
69
72.30
0.95(0.74–1.21)
Second breast
1,906
8,947.89
20
0.38
52.12 (31.83–80.49)
Colorectal
1,926
9,025.49
26
22.64
1.15 (0.75–1.68)
Lung and bronchus
1,926
9,065.75
23
32.76
0.70 (0.45–1.05)
Bladder
1,926
9,031.02
20
13.46
1.49 (0.91–2.29)
Melanomaa
1,454
6,971.11
14
4.69
2.98 (1.63–5.00)
Stomach
1,926
9,074.43
10
4.74
2.11 (1.01–3.88)

Bold numbers indicate that the 95 percent confidence interval (CI) does not include 1.00. aNon-Hispanic whites only. EXP, expected; N, number of subjects; OBS, observed; PERYR, person years at risk; SIR, standardized incidence ratios.

Satram-Hoang et al. Breast Cancer Research 2007 9:R10   doi:10.1186/bcr1643