Table 3

Risk of second primary cancer by age at first primary male breast cancer diagnosis


Age (years)

Cancer site
<60
60 to 69
≥70


N
PERYR
OBS
EXP
SIR (95 percent CI)
N
PERYR
OBS
EXP
SIR (95 percent CI)
N
PERYR
OBS
EXP
SIR (95 percent CI)

All, breast included
618
2,912.85
41
28.08
1.42 (1.02–1.94)
547
2,681.23
89
72.35
1.24 (1.00–1.53)
761
2,866.01
91
89.99
1.01 (0.81–1.24)
All, breast excluded
618
2,929.25
36
28.29
1.24 (0.86–1.72)
547
2,716.56
80
73.08
1.11 (0.88–1.38)
761
2,883.83
85
90.26
0.94 (0.75–1.16)
Prostate
618
2,982.99
15
8.41
1.78 (1.00–2.94)
547
2,826.47
27
29.32
0.92 (0.61–1.34)
761
2,994.29
27
34.56
0.78 (0.51–1.14)
Second breast
605
2,992.73
5
0.06
81.38 (26.42–189.92)
543
2,871.22
9
0.14
64.23 (29.37–121.92)
758
3,083.94
6
0.18
32.98 (12.09–71.68)
Colorectal
618
3,047.87
3
3.11
0.96 (0.20–2.82)
547
2,891.37
15
8.19
1.83 (1.03–3.02)
761
3,086.25
8
11.34
0.71 (0.30–1.39)
Lung and bronchus
618
3,053.53
3
5.15
0.58 (0.12–1.70)
547
2,902.69
13
12.81
1.02 (0.54–1.74)
761
3,109.52
7
14.80
0.47 (0.19–0.97)
Bladder
618
3,041.90
3
1.62
1.85 (0.38–5.41)
547
2,901.04
6
4.87
1.23 (0.45–2.68)
761
3,088.07
11
6.97
1.58 (0.79–2.82)
Melanomaa
419
2,166.33
3
1.09
2.74 (0.57–8.01)
427
2,358.83
5
1.72
2.92 (0.95–6.80)
686
2,445.95
6
1.89
3.18 (1.17–6.93)
Stomach
618
3,054.70
0
0.66
0.00 (0.00–4.54)
547
2,909.55
4
1.66
2.41 (0.66–6.16)
761
3,110.18
6
2.42
2.48 (0.91–5.40)

Bold numbers indicate that the 95 percent confidence interval (CI) does not include 1.00. aNon-Hispanic whites only. EXP, expected; N, number of subjects; OBS, observed; PERYR, person years at risk; SIR, standardized incidence ratios.

Satram-Hoang et al. Breast Cancer Research 2007 9:R10   doi:10.1186/bcr1643