Table 3 |
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|
Risk of second primary cancer by age at first primary male breast cancer diagnosis |
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| Age (years) |
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|
|
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| Cancer site |
<60 |
60 to 69 |
≥70 |
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|
|
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| N |
PERYR |
OBS |
EXP |
SIR (95 percent CI) |
N |
PERYR |
OBS |
EXP |
SIR (95 percent CI) |
N |
PERYR |
OBS |
EXP |
SIR (95 percent CI) |
|
|
|
|||||||||||||||
| All, breast included |
618 |
2,912.85 |
41 |
28.08 |
1.42 (1.02–1.94) |
547 |
2,681.23 |
89 |
72.35 |
1.24 (1.00–1.53) |
761 |
2,866.01 |
91 |
89.99 |
1.01 (0.81–1.24) |
| All, breast excluded |
618 |
2,929.25 |
36 |
28.29 |
1.24 (0.86–1.72) |
547 |
2,716.56 |
80 |
73.08 |
1.11 (0.88–1.38) |
761 |
2,883.83 |
85 |
90.26 |
0.94 (0.75–1.16) |
| Prostate |
618 |
2,982.99 |
15 |
8.41 |
1.78 (1.00–2.94) |
547 |
2,826.47 |
27 |
29.32 |
0.92 (0.61–1.34) |
761 |
2,994.29 |
27 |
34.56 |
0.78 (0.51–1.14) |
| Second breast |
605 |
2,992.73 |
5 |
0.06 |
81.38 (26.42–189.92) |
543 |
2,871.22 |
9 |
0.14 |
64.23 (29.37–121.92) |
758 |
3,083.94 |
6 |
0.18 |
32.98 (12.09–71.68) |
| Colorectal |
618 |
3,047.87 |
3 |
3.11 |
0.96 (0.20–2.82) |
547 |
2,891.37 |
15 |
8.19 |
1.83 (1.03–3.02) |
761 |
3,086.25 |
8 |
11.34 |
0.71 (0.30–1.39) |
| Lung and bronchus |
618 |
3,053.53 |
3 |
5.15 |
0.58 (0.12–1.70) |
547 |
2,902.69 |
13 |
12.81 |
1.02 (0.54–1.74) |
761 |
3,109.52 |
7 |
14.80 |
0.47 (0.19–0.97) |
| Bladder |
618 |
3,041.90 |
3 |
1.62 |
1.85 (0.38–5.41) |
547 |
2,901.04 |
6 |
4.87 |
1.23 (0.45–2.68) |
761 |
3,088.07 |
11 |
6.97 |
1.58 (0.79–2.82) |
| Melanomaa |
419 |
2,166.33 |
3 |
1.09 |
2.74 (0.57–8.01) |
427 |
2,358.83 |
5 |
1.72 |
2.92 (0.95–6.80) |
686 |
2,445.95 |
6 |
1.89 |
3.18 (1.17–6.93) |
| Stomach |
618 |
3,054.70 |
0 |
0.66 |
0.00 (0.00–4.54) |
547 |
2,909.55 |
4 |
1.66 |
2.41 (0.66–6.16) |
761 |
3,110.18 |
6 |
2.42 |
2.48 (0.91–5.40) |
|
|
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|
Bold numbers indicate that the 95 percent confidence interval (CI) does not include 1.00. aNon-Hispanic whites only. EXP, expected; N, number of subjects; OBS, observed; PERYR, person years at risk; SIR, standardized incidence ratios. |
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|
Satram-Hoang et al. Breast Cancer Research 2007 9:R10 doi:10.1186/bcr1643 |
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