Table 5

Risk of second primary cancer by time after first primary male breast cancer


<1 year
1 to 5 years
>5 years

Cancer site
N
PERYR
OBS
EXP
SIR (95 percent CI)
N
PERYR
OBS
EXP
SIR (95 percent CI)
N
PERYR
OBS
EXP
SIR (95 percent CI)

All, breast included
1,926
1,653.87
42
57.12
0.74 (0.53–0.99)
1,884
4332.66
88
101.51
0.87 (0.70–1.07)
1,796
2,469.34
91
55.92
1.63 (1.31–2.00)
All, breast excluded
1,926
1,655.89
38
57.09
0.67 (0.47–0.91)
1,888
4359.60
81
101.92
0.79 (0.63–0.99)
1,807
2,509.90
82
56.64
1.45 (1.15–1.80)
Prostate
1,926
1,666.28
14
20.83
0.67 (0.37–1.13)
1,912
4450.10
27
37.81
0.71 (0.47–1.04)
1,885
2,683.08
28
21.89
1.28 (0.85–1.85)
Second breast
1,926
1,654.10
4
0.11
34.90 (9.51–89.35)
1,922
4478.09
7
0.21
33.77 (13.58–69.57)
1,915
2,811.43
9
0.12
75.85 (34.68–143.99)
Colorectal
1,926
1,670.38
5
6.23
0.80 (0.26–1.87)
1,921
4524.94
11
11.66
0.94 (0.47–1.69)
1,910
2,825.87
10
7.11
1.41 (0.67–2.59)
Lung and bronchus
1,926
1,672.78
4
9.23
0.43 (0.12–1.11)
1,922
4540.41
6
17.21
0.35 (0.13–0.76)
1,916
2,848.25
13
10.82
1.20 (0.64–2.05)
Bladder
1,926
1,671.12
4
3.73
1.07 (0.29–2.74)
1,922
4534.16
4
6.97
0.57 (0.16–1.47)
1,918
2,821.43
12
4.15
2.89 (1.49–5.05)
Melanomaa
1,454
1,276.50
1
1.48
0.68 (0.02–3.77)
1,453
3491.48
7
2.61
2.68 (1.08–5.53)
1,446
2,199.81
6
1.45
4.15 (1.52–9.02)
Stomach
1,926
1,672.98
2
1.30
1.54 (0.19–5.58)
1,924
4545.53
4
2.43
1.65 (0.45–4.21)
1,920
2,851.61
4
1.50
2.66 (0.72–6.81)
Age (years)















     <60
618
531.05
6
5.85
1.02 (0.38–2.23)
612
1445.16
12
12.41
0.89 (0.44–1.59)
600
935.26
23
8.18
2.81 (1.78–4.22)
     60 to 69
547
491.85
7
18.38
0.38 (0.15–0.78)
540
1329.22
36
35.41
1.04 (0.74–1.44)
504
858.89
46
23.64
1.95 (1.42–2.60)
     70+
761
630.97
29
32.89
0.88 (0.59–1.27)
732
1558.27
40
53.69
0.74 (0.53–1.01)
692
675.19
22
24.10
0.91 (0.57–1.38)

Bold numbers indicate that the 95 percent confidence interval (CI) does not include 1.00. aNon-Hispanic whites only. EXP, expected; N, number of subjects; OBS, observed; PERYR, person years at risk; SIR, standardized incidence ratios.

Satram-Hoang et al. Breast Cancer Research 2007 9:R10   doi:10.1186/bcr1643