Table 5 |
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|
Risk of second primary cancer by time after first primary male breast cancer |
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| <1 year |
1 to 5 years |
>5 years |
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|
|
|||||||||||||||
| Cancer site |
N |
PERYR |
OBS |
EXP |
SIR (95 percent CI) |
N |
PERYR |
OBS |
EXP |
SIR (95 percent CI) |
N |
PERYR |
OBS |
EXP |
SIR (95 percent CI) |
|
|
|||||||||||||||
| All, breast included |
1,926 |
1,653.87 |
42 |
57.12 |
0.74 (0.53–0.99) |
1,884 |
4332.66 |
88 |
101.51 |
0.87 (0.70–1.07) |
1,796 |
2,469.34 |
91 |
55.92 |
1.63 (1.31–2.00) |
| All, breast excluded |
1,926 |
1,655.89 |
38 |
57.09 |
0.67 (0.47–0.91) |
1,888 |
4359.60 |
81 |
101.92 |
0.79 (0.63–0.99) |
1,807 |
2,509.90 |
82 |
56.64 |
1.45 (1.15–1.80) |
| Prostate |
1,926 |
1,666.28 |
14 |
20.83 |
0.67 (0.37–1.13) |
1,912 |
4450.10 |
27 |
37.81 |
0.71 (0.47–1.04) |
1,885 |
2,683.08 |
28 |
21.89 |
1.28 (0.85–1.85) |
| Second breast |
1,926 |
1,654.10 |
4 |
0.11 |
34.90 (9.51–89.35) |
1,922 |
4478.09 |
7 |
0.21 |
33.77 (13.58–69.57) |
1,915 |
2,811.43 |
9 |
0.12 |
75.85 (34.68–143.99) |
| Colorectal |
1,926 |
1,670.38 |
5 |
6.23 |
0.80 (0.26–1.87) |
1,921 |
4524.94 |
11 |
11.66 |
0.94 (0.47–1.69) |
1,910 |
2,825.87 |
10 |
7.11 |
1.41 (0.67–2.59) |
| Lung and bronchus |
1,926 |
1,672.78 |
4 |
9.23 |
0.43 (0.12–1.11) |
1,922 |
4540.41 |
6 |
17.21 |
0.35 (0.13–0.76) |
1,916 |
2,848.25 |
13 |
10.82 |
1.20 (0.64–2.05) |
| Bladder |
1,926 |
1,671.12 |
4 |
3.73 |
1.07 (0.29–2.74) |
1,922 |
4534.16 |
4 |
6.97 |
0.57 (0.16–1.47) |
1,918 |
2,821.43 |
12 |
4.15 |
2.89 (1.49–5.05) |
| Melanomaa |
1,454 |
1,276.50 |
1 |
1.48 |
0.68 (0.02–3.77) |
1,453 |
3491.48 |
7 |
2.61 |
2.68 (1.08–5.53) |
1,446 |
2,199.81 |
6 |
1.45 |
4.15 (1.52–9.02) |
| Stomach |
1,926 |
1,672.98 |
2 |
1.30 |
1.54 (0.19–5.58) |
1,924 |
4545.53 |
4 |
2.43 |
1.65 (0.45–4.21) |
1,920 |
2,851.61 |
4 |
1.50 |
2.66 (0.72–6.81) |
| Age (years) |
|||||||||||||||
| <60 |
618 |
531.05 |
6 |
5.85 |
1.02 (0.38–2.23) |
612 |
1445.16 |
12 |
12.41 |
0.89 (0.44–1.59) |
600 |
935.26 |
23 |
8.18 |
2.81 (1.78–4.22) |
| 60 to 69 |
547 |
491.85 |
7 |
18.38 |
0.38 (0.15–0.78) |
540 |
1329.22 |
36 |
35.41 |
1.04 (0.74–1.44) |
504 |
858.89 |
46 |
23.64 |
1.95 (1.42–2.60) |
| 70+ |
761 |
630.97 |
29 |
32.89 |
0.88 (0.59–1.27) |
732 |
1558.27 |
40 |
53.69 |
0.74 (0.53–1.01) |
692 |
675.19 |
22 |
24.10 |
0.91 (0.57–1.38) |
|
|
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|
Bold numbers indicate that the 95 percent confidence interval (CI) does not include 1.00. aNon-Hispanic whites only. EXP, expected; N, number of subjects; OBS, observed; PERYR, person years at risk; SIR, standardized incidence ratios. |
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|
Satram-Hoang et al. Breast Cancer Research 2007 9:R10 doi:10.1186/bcr1643 |
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