Table 1

Tumorigenesis in short-term hormone-treated mice

Experiment

Group

Tumors/transplants (percentage)

Percentage inhibition

Experiment duration (weeks)

1/1A

Untreated

16/66 (24)

-

45

E/P (5–7)

2/66 (03)^a

87.5

45

2

Untreated

10/20 (50)

-

48

E/P (5–7)

3/20 (15)^a

70

48

E/P (23–25)

4/20 (20)^a

60

48

Tamoxifen (11–24)

0/20 (0)^a

100

48

3

Untreated, trans. (3)

9/20 (45)

-

58

E/P (5–7), trans. (3)

3/15 (20)^a

56

58

Untreated, trans. (11)

9/20 (45)

-

58

E+P (5–7), trans. (11)

4/20 (20)^a

56

58

4

Untreated

15/15^b (100)

24

E/P

6/15^b (37) ^a

63

32

E

5/15^b (33) ^a

67

32

E, estrogen; P, progesterone; trans., transplantation. ^ap < 0.05; ^bin this experiment, the column refers to the number of tumor-bearing mice/total number of mice.

Rajkumar et al. Breast Cancer Research 2007 9:R12   doi:10.1186/bcr1645