Table 1

Tumorigenesis in short-term hormone-treated mice

Experiment
Group
Tumors/transplants (percentage)
Percentage inhibition
Experiment duration (weeks)

1/1A
Untreated
16/66 (24)
-
45

E/P (5–7)
2/66 (03)a
87.5
45
2
Untreated
10/20 (50)
-
48

E/P (5–7)
3/20 (15)a
70
48

E/P (23–25)
4/20 (20)a
60
48

Tamoxifen (11–24)
0/20 (0)a
100
48
3
Untreated, trans. (3)
9/20 (45)
-
58

E/P (5–7), trans. (3)
3/15 (20)a
56
58

Untreated, trans. (11)
9/20 (45)
-
58

E+P (5–7), trans. (11)
4/20 (20)a
56
58
4
Untreated
15/15b (100)

24

E/P
6/15b (37) a
63
32

E
5/15b (33) a
67
32

E, estrogen; P, progesterone; trans., transplantation. ap < 0.05; bin this experiment, the column refers to the number of tumor-bearing mice/total number of mice.

Rajkumar et al. Breast Cancer Research 2007 9:R12   doi:10.1186/bcr1645

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