|
Cytokine levels are correlated to AP-1 expression |
|||||
| Biological markers |
AP-1 negative (n = 34) |
AP-1 positive (n = 69) |
P |
||
|
|
|||||
| IL-1β |
1.4 |
(0–11.5) |
3.2 |
(0–260) |
0.006 |
| IL-2 |
0.4 |
(0–3.2) |
1.4 |
(0–11) |
0.001 |
| IL-4 |
1.1 |
(0–99.6) |
2.7 |
(0–30.2) |
NS |
| IL-6 |
12.6 |
(4.4–70.7) |
19.7 |
(7.8–26,487) |
0.001 |
| IL-8 |
29.6 |
(0 -778) |
115 |
(1.5–15,890) |
0.003 |
| IL-10 |
0.2 |
(0–2.6) |
0.3 |
(0– 5.6) |
0.004 |
| IL-12 (p70) |
1.8 |
(0 -17.2) |
2.7 |
(0–7.3) |
0.044 |
| IL-13 |
4.2 |
(3.0–7.2) |
4.2 |
(3.4–394) |
NS |
| G-CSF |
17.2 |
(5.3–87.3) |
18.5 |
(7.1–110) |
NS |
| IFN-γ |
25.4 |
(15.5–55.5) |
28.7 |
(17.1–1,279) |
0.002 |
| MCP-1 |
54.6 |
(0–1,208) |
148 |
(14.7–37,117) |
0.001 |
| MIP-1β |
503 |
(87.2–8,778) |
563 |
(42.6–14,439) |
NS |
| TNF-α |
6.9 |
(6.1–10.9) |
7.8 |
(5.8–121) |
0.002 |
|
Values are expressed as median (range; fg/μg). AP, activator protein; G-CSF, granulocyte colony-stimulating factor; IL, interleukin; IFN, interferon; MCP, monocyte chemoattractant protein; MIP, macrophage inflammatory protein; NS, not significant; TNF, tumour necrosis factor. | |||||
Chavey et al. Breast Cancer Research 2007 9:R15 doi:10.1186/bcr1648 |
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