Breast Cancer Research

official impact factor 5.79

Open Access Highly Access Research article

Basal-like phenotype is not associated with patient survival in estrogen-receptor-negative breast cancers

Mervi Jumppanen1,2*, Sofia Gruvberger-Saal3, Päivikki Kauraniemi2, Minna Tanner4,2, Pär-Ola Bendahl3, Mikael Lundin5, Morten Krogh6, Pasi Kataja2, Åke Borg3, Mårten Fernö3 and Jorma Isola2

Author Affiliations

1 Department of Pathology, Seinäjoki Central Hospital, Hanneksenrinne 7, FIN-60220 Seinäjoki, Finland

2 Institute of Medical Technology, University and University Hospital of Tampere, Biokatu 6, FIN-33520 Tampere, Finland

3 Department of Oncology, Clinical Sciences, University of Lund, Klinikgatan 7, SE-221 85 Lund, Sweden

4 Department of Oncology, Tampere University Hospital, Teiskontie 35, FIN-33520 Tampere, Finland

5 Biomedical Informatics group, Department of Oncology, University of Helsinki, Haartmanninkatu 8, FIN-00290 Helsinki, Finland

6 Department of Theoretical Physics, Lund University, Sölvegatan 14A, SE-221 85 Lund, Sweden

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Breast Cancer Research 2007, 9:R16 doi:10.1186/bcr1649

Published: 31 January 2007

Additional files

Additional File 1:

A PDF file containing a heat map of 50 ER-negative tumors based on the top 500 gene set generated for the CK5/14-positive tumors. Yellow indicates the basal-like cluster and black the non-basal-like cluster.

Format: PDF Size: 928KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional File 2:

An Excel file containing the top 200 genes list generated for the immunohistochemically CK5/14-positive ER-negative breast cancers. The membrane association is defined.

Format: XLS Size: 75KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional File 3:

A PDF file containing a heat map of 50 ER-negative tumors based on the intrinsic gene set by Sorlie and colleagues [7]. Yellow indicates the basal-like cluster and black the non-basal-like cluster.

Format: PDF Size: 996KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data

Additional File 4:

A PDF file containing the results of a gene ontology annotation analysis of the top 1,000 basal genes.

Format: PDF Size: 92KB Download file

This file can be viewed with: Adobe Acrobat Reader

Open Data