Table 2

Overall survival and disease-free survival data for all tumours

Parameter

Overall survival

Disease-free survival

Survival from recurrence


5-year

Hazard ratio (95% CI)

p value

5-year

Hazard ratio (95% CI)

p value

Hazard ratio (95% CI)

p value


Axillary metastases

No

71%

1.0

<0.0001

65%

1.0

<0.0001

1.0

0.32

Yes

51%

1.83 (1.44–2.33)

41%

1.83 (1.45–2.32)

1.17 (0.86–1.57)

Tumour size

p1

89%

1.0

0.002

70%

1.0

0.0005

1.0

0.26

p2

61%

1.54 (0.92–2.62)

54%

1.49 (0.90–2.48)

1.09 (0.60–1.96)

p3

46%

2.18 (1.25–3.82)

35%

2.20 (1.28–3.79)

1.29 (0.69–2.41)

ER

Positive

64%

1.0

0.68

52%

1.0

0.74

1.0

<0.0001

Negative

52%

1.05 (0.83–1.33)

48%

0.96 (0.76–1.21)

2.1 (1.59–2.79)

PR

Positive

64%

1.0

0.82

49%

1.0

0.55

1.0

0.005

Negative

56%

1.03 (0.80–1.33)

52%

0.93 (0.72–1.19)

1.51 (1.13–2.02)

Age in years

<35

53%

1.0

0.002

39%

1.0

0.01

1.0

0.96

35–50

58%

0.90 (0.57–1.41)

50%

0.99 (0.63–1.55)

0.89 (0.57–1.39)

50–65

64%

0.81 (0.52–1.26)

57%

0.85 (0.55–1.31)

0.89 (0.57–1.38)

>65

54%

1.44 (0.90–2.30)

44%

1.39 (0.87–2.23)

0.89 (0.52–1.50)

CK14

Negative

59%

1.0

0.02

49%

1.0

0.005

1.0

0.001

Positive

60%

0.69 (0.50–0.94)

56%

0.65 (0.48–0.88)

1.84 (1.27–2.65)

CK14 pattern

Negative

59%

1.0

0.005

49%

1.0

0.003

1.0

0.002

Focal

50%

0.92 (0.65–1.28)

48%

0.83 (0.59–1.16)

2.31 (1.54–3.45)

Diffuse

88%

0.31 (0.15–0.63)

79%

0.32 (0.17–0.63)

0.84 (0.35–2.06)


Tumour sizes: p1, <2 cm; p2, 2–5 cm; p3, >5 cm. CI, confidence interval; CK14, cytokeratin 14; ER, oestrogen receptor; PR, progesterone receptor.

Fulford et al. Breast Cancer Research 2007 9:R4   doi:10.1186/bcr1636

Open Data