Table 1 |
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|
Selected characteristics among breast cancer cases by hormone receptor status: SEER program, 1990–2001 |
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| ER+PR+ |
ER+PR- |
ER-PR+ |
ER-PR- |
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| (n = 98,463) |
(n = 19,886) |
(n = 4,896) |
(n = 31,930) |
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|
|
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| Characteristics |
n |
Column % |
Row % |
n |
Column % |
Row % |
n |
Column % |
Row % |
n |
Column % |
Row % |
|
|
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| Age at diagnosis, years |
||||||||||||
| 30–39 |
4,903 |
5.0 |
49.5 |
885 |
4.5 |
8.9 |
569 |
11.6 |
5.7 |
3,558 |
11.1 |
35.9 |
| 40–49 |
18,575 |
18.9 |
60.9 |
2,490 |
12.5 |
8.2 |
1,508 |
30.8 |
4.9 |
7,929 |
24.8 |
26.0 |
| 50–59 |
21,807 |
22.1 |
61.4 |
4,464 |
22.5 |
12.5 |
1,161 |
23.7 |
3.3 |
8,094 |
25.4 |
22.8 |
| 60–69 |
22,019 |
22.4 |
65.9 |
4,752 |
23.9 |
14.2 |
801 |
16.4 |
2.4 |
5,856 |
18.3 |
17.5 |
| 70–79 |
20,667 |
21.0 |
68.2 |
4,662 |
23.4 |
15.4 |
584 |
11.9 |
1.9 |
4,401 |
13.8 |
14.5 |
| ≥80 |
10,492 |
10.6 |
67.7 |
2,633 |
13.2 |
17.0 |
273 |
5.6 |
1.8 |
2,092 |
6.6 |
13.5 |
| Diagnosis year |
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| 1990–1992 |
16,500 |
16.8 |
61.6 |
3,751 |
18.9 |
14.0 |
1,111 |
22.7 |
4.1 |
5,435 |
17.0 |
20.3 |
| 1993–1995 |
22,087 |
22.4 |
61.7 |
4,514 |
22.7 |
12.6 |
1,485 |
30.3 |
4.1 |
7,728 |
24.2 |
21.6 |
| 1996–1998 |
27,734 |
28.2 |
64.2 |
5,239 |
26.3 |
12.1 |
1,367 |
27.9 |
3.2 |
8,884 |
27.8 |
20.5 |
| 1999–2001 |
32,142 |
32.6 |
65.2 |
6,382 |
32.1 |
12.9 |
933 |
19.1 |
1.9 |
9,883 |
31.0 |
20.0 |
| SEER registry |
||||||||||||
| Atlanta, GA |
5,696 |
5.8 |
59.4 |
1,171 |
5.9 |
12.2 |
381 |
7.8 |
4 |
2,344 |
7.3 |
24.4 |
| Connecticut |
11,093 |
11.3 |
61.4 |
2,448 |
12.3 |
13.6 |
602 |
12.3 |
3.3 |
3,914 |
12.3 |
21.7 |
| Detroit, MI |
10,559 |
10.7 |
60.4 |
2,314 |
11.6 |
13.2 |
539 |
11 |
3.1 |
4,063 |
12.7 |
23.3 |
| Hawaii |
4,149 |
4.2 |
67.0 |
703 |
3.5 |
11.3 |
273 |
5.6 |
4.4 |
1,072 |
3.4 |
17.3 |
| Iowa |
10,238 |
10.4 |
65.2 |
1,914 |
9.6 |
12.2 |
530 |
10.8 |
3.4 |
3,017 |
9.4 |
19.2 |
| Los Angeles, CA |
15,586 |
15.8 |
61.4 |
3,399 |
17.1 |
13.4 |
919 |
18.8 |
3.6 |
5,491 |
17.2 |
21.6 |
| New Mexico |
4,066 |
4.1 |
61.8 |
885 |
4.5 |
13.5 |
193 |
3.9 |
2.9 |
1,435 |
4.5 |
21.8 |
| San Francisco-Oakland, CA |
13,063 |
13.3 |
63.9 |
2,750 |
13.8 |
13.5 |
652 |
13.3 |
3.2 |
3,957 |
12.4 |
19.4 |
| San Jose, CA |
5,474 |
5.5 |
65.3 |
1,134 |
5.7 |
13.5 |
228 |
4.7 |
2.7 |
1,548 |
4.9 |
18.5 |
| Seattle, WA |
14,241 |
14.5 |
68 |
2,517 |
12.7 |
12.0 |
423 |
8.6 |
2.0 |
3,770 |
11.8 |
18.0 |
| Utah |
4,298 |
4.4 |
66.9 |
651 |
3.3 |
10.1 |
156 |
3.2 |
2.5 |
1,319 |
4.1 |
20.5 |
| Race |
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| Non-Hispanic white |
78,805 |
81.7 |
65.4 |
15,716 |
80.5 |
13.0 |
3,515 |
73.5 |
2.9 |
22,532 |
72.1 |
18.7 |
| African-American |
5,724 |
5.9 |
48.0 |
1,488 |
7.6 |
12.5 |
504 |
10.5 |
4.2 |
4,206 |
13.5 |
35.3 |
| Native American |
284 |
0.3 |
55.0 |
57 |
0.3 |
11.0 |
23 |
0.5 |
4.5 |
152 |
0.5 |
29.5 |
| Asian/Pacific Islander |
6,065 |
6.3 |
65.1 |
1,061 |
5.4 |
11.4 |
382 |
8.0 |
4.1 |
1,805 |
5.8 |
19.4 |
| Hispanic white |
5,585 |
5.8 |
57.8 |
1,203 |
6.2 |
12.4 |
359 |
7.5 |
3.7 |
2,524 |
8.1 |
26.1 |
| Other/Unknown |
2,000 |
- |
- |
361 |
- |
- |
113 |
- |
- |
711 |
- |
- |
| Tumor histology |
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| Ductal |
71,199 |
72.3 |
62.7 |
13,981 |
70.3 |
12.3 |
3,641 |
74.4 |
3.2 |
24,722 |
77.4 |
21.8 |
| Lobular |
8,980 |
9.1 |
73.6 |
2,160 |
10.9 |
17.7 |
283 |
5.8 |
2.3 |
784 |
2.5 |
6.4 |
| Ductal/Lobular |
7,576 |
7.7 |
76.7 |
1,341 |
6.7 |
13.6 |
233 |
4.8 |
2.4 |
722 |
2.3 |
7.3 |
| Inflammatory |
543 |
0.5 |
37.8 |
191 |
1.0 |
13.3 |
90 |
1.8 |
6.3 |
611 |
1.9 |
42.6 |
| Mucinous |
2,927 |
3.0 |
80.9 |
486 |
2.4 |
13.5 |
41 |
0.8 |
1.1 |
164 |
0.5 |
4.5 |
| Tubular |
1,696 |
1.7 |
79 |
327 |
1.6 |
15.2 |
44 |
0.9 |
2.1 |
79 |
0.3 |
3.7 |
| Comedo |
1,159 |
1.2 |
43.6 |
318 |
1.6 |
12.0 |
179 |
3.6 |
6.7 |
1,003 |
3.1 |
37.7 |
| Medullary |
266 |
0.3 |
14.7 |
148 |
0.8 |
8.2 |
97 |
2.0 |
5.4 |
1,292 |
4.0 |
71.7 |
| Papillary |
582 |
0.6 |
79.0 |
58 |
0.3 |
7.9 |
10 |
0.2 |
1.3 |
87 |
0.3 |
11.8 |
| Other |
3,535 |
3.6 |
49.4 |
876 |
4.4 |
12.2 |
278 |
5.7 |
3.9 |
2,466 |
7.7 |
34.5 |
| Tumor stage |
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| I |
50,172 |
52.4 |
69.2 |
9,232 |
48 |
12.7 |
1,999 |
42.7 |
2.8 |
11,114 |
36.2 |
15.3 |
| II |
37,335 |
39.0 |
60.3 |
7,606 |
39.5 |
12.3 |
2,068 |
44.2 |
3.3 |
14,878 |
48.4 |
24.1 |
| III |
5,332 |
5.5 |
51.3 |
1,471 |
7.6 |
14.1 |
385 |
8.2 |
3.7 |
3,210 |
10.4 |
30.9 |
| IV |
2,943 |
3.1 |
52.1 |
936 |
4.9 |
16.6 |
230 |
4.9 |
4.1 |
1,536 |
5.0 |
27.2 |
| Unstaged |
2,681 |
- |
- |
641 |
- |
- |
214 |
- |
- |
1,192 |
- |
- |
| Tumor grade |
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| 1 |
18,012 |
21.8 |
81.1 |
2,885 |
17.5 |
13.0 |
405 |
9.9 |
1.8 |
914 |
3.3 |
4.1 |
| 2 |
40,642 |
49.3 |
74.2 |
7,133 |
43.4 |
13.0 |
1,324 |
32.5 |
2.4 |
5,682 |
20.6 |
10.4 |
| 3 |
22,082 |
26.8 |
44.4 |
6,027 |
36.6 |
12.1 |
2,174 |
53.3 |
4.4 |
19,412 |
70.4 |
39.1 |
| 4 |
1,774 |
2.1 |
45.0 |
413 |
2.5 |
10.5 |
173 |
4.3 |
4.4 |
1,579 |
5.7 |
40.1 |
| Unknown |
15,953 |
- |
3,428 |
- |
820 |
- |
4,343 |
- |
||||
| Tumor size (cm) |
||||||||||||
| 0–1.9 |
56,547 |
59.9 |
69.2 |
10,302 |
54.6 |
12.6 |
2,271 |
49.5 |
2.8 |
12,576 |
41.8 |
15.4 |
| 2–5 |
32,977 |
34.9 |
58.7 |
7,135 |
37.8 |
12.7 |
1,891 |
41.3 |
3.4 |
14,147 |
47.1 |
25.2 |
| >5 |
4,949 |
5.2 |
48.8 |
1,432 |
7.6 |
14.1 |
422 |
9.2 |
4.2 |
3,330 |
11.1 |
32.9 |
| Unknown |
3,990 |
- |
- |
1,017 |
- |
- |
312 |
- |
- |
1,877 |
- |
- |
| Axillary lymph node status |
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| Negative |
54,948 |
65.3 |
64.8 |
10,428 |
63.0 |
12.3 |
2,622 |
61.0 |
3.1 |
16,749 |
60.3 |
19.8 |
| Positive |
29,234 |
34.7 |
60.9 |
6,110 |
37.0 |
12.7 |
1,675 |
39.0 |
3.5 |
11,015 |
39.7 |
22.9 |
| Unknown |
14,281 |
- |
- |
3,348 |
- |
- |
599 |
- |
- |
4,166 |
- |
- |
| Surgical treatment |
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| Performed |
96,387 |
98.0 |
63.7 |
19,216 |
96.7 |
12.7 |
4,764 |
97.4 |
3.2 |
30,847 |
96.8 |
20.4 |
| Not performed |
2,012 |
2.0 |
52.7 |
648 |
3.3 |
17.0 |
126 |
2.6 |
3.3 |
1,032 |
3.2 |
27 |
| Unknown |
64 |
- |
- |
22 |
- |
- |
6 |
- |
- |
51 |
- |
- |
| Radiation therapy |
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| Treated |
46,859 |
48.5 |
65.5 |
8,694 |
44.5 |
12.1 |
2,048 |
42.9 |
2.9 |
13,922 |
44.8 |
19.5 |
| None |
49,776 |
51.5 |
61.9 |
10,836 |
55.5 |
13.4 |
2,725 |
57.1 |
3.4 |
17,131 |
55.2 |
21.3 |
| Unknown |
1,828 |
- |
- |
356 |
- |
- |
123 |
- |
- |
877 |
- |
- |
|
|
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|
ER, estrogen receptor; PR, progesterone receptor; SEER, Surveillance, Epidemiology, and End Results. |
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|
Dunnwald et al. Breast Cancer Research 2007 9:R6 doi:10.1186/bcr1639 |
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