Breast Cancer Research

official impact factor 5.79

An international initiative to identify genetic modifiers of cancer risk in BRCA1 and BRCA2 mutation carriers: the Consortium of Investigators of Modifiers of BRCA1 and BRCA2 (CIMBA)

Georgia Chenevix-Trench*, Roger L Milne, Antonis C Antoniou, Fergus J Couch, Douglas F Easton, David E Goldgar and CIMBA

Breast Cancer Research 2007, 9:104 doi:10.1186/bcr1670

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Common breast cancer susceptibility alleles are associated with tumour subtypes in BRCA1 and BRCA2 mutation carriers: results from the Consortium of Investigators of Modifiers of BRCA1/2

Anna Mulligan, Fergus J Couch, Daniel Barrowdale, Susan M Domchek, Diana Eccles, Heli Nevanlinna, Susan J Ramus, Mark Robson, Mark Sherman, Amanda B Spurdle, Barbara Wappenschmidt, Andrew Lee, Lesley McGuffog, Sue Healey, Olga M Sinilnikova, Ramunas Janavicius, Thomas Hansen, Finn C Nielsen, Bent Ejlertsen, Ana Osorio et al. Breast Cancer Research 2011, 13:R110 (2 November 2011)

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Penetrance estimates for BRCA1 and BRCA2 based on genetic testing in a Clinical Cancer Genetics service setting: Risks of breast/ovarian cancer quoted should reflect the cancer burden in the family

D Gareth Evans, Andrew Shenton, Emma Woodward, Fiona Lalloo, Anthony Howell, Eamonn R Maher BMC Cancer 2008, 8:155 (30 May 2008)

Counselling about the risks of breast and ovarian cancer for women who carry a BRCA1 or BRCA2 mutation should take into account the family history, because these women have a higher risk of cancer than the average population risk indicates.