Table 1 |
|||
|
Simulated power (%) to detect a polymorphism with varying minor allele frequency and risk ratio, under a multiplicative model at a significance level 10-4 |
|||
|
Minor allele frequency |
Relative hazard |
Sample size: 5000 |
Sample size: 10,000 |
|
|
|||
|
0.10 |
1.1 |
2 |
7 |
|
1.2 |
33 |
80 |
|
|
1.3 |
86 |
100 |
|
|
0.20 |
1.1 |
5 |
26 |
|
1.2 |
74 |
100 |
|
|
1.3 |
100 |
100 |
|
|
0.30 |
1.1 |
10 |
44 |
|
1.2 |
89 |
100 |
|
|
1.3 |
100 |
100 |
|
|
|
|||
|
Simulations performed as in [5]. |
|||
|
Chenevix-Trench et al. Breast Cancer Research 2007 9:104 doi:10.1186/bcr1670 |
|||