Breast Cancer Research

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Expression genomics in breast cancer research: microarrays at the crossroads of biology and medicine

Lance D Miller* and Edison T Liu

Breast Cancer Research 2007, 9:206 doi:10.1186/bcr1662

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Methodology article   Open Access Highly Accessed

A kinetic-based sigmoidal model for the polymerase chain reaction and its application to high-capacity absolute quantitative real-time PCR

Robert G Rutledge, Don Stewart BMC Biotechnology 2008, 8:47 (8 May 2008)

Abstract | Full text | PDF | PubMed | Cited on BioMed Central | 1 comment |  Editor’s summary

The LRE (linear regression of efficiency) algorithm for estimating PCR efficiency is a kinetic-based sigmoidal approach that, when coupled with optical calibration, provides data comparison without using standard curves, allowing high-capacity absolute PCR quantification.

Research   Open Access Highly Accessed

Genome-wide expression patterns of invasion front, inner tumor mass and surrounding normal epithelium of colorectal tumors

Eike Staub, Joern Groene, Maya Heinze, Detlev Mennerich, Stefan Roepcke, Irina Klaman, Bernd Hinzmann, Esmeralda Castanos-Velez, Christian Pilarsky, Benno Mann, Thomas Brümmendorf, Birgit Weber, Heinz-Johannes Buhr, André Rosenthal Molecular Cancer 2007, 6:79 (14 December 2007)

Abstract | Full text | PDF | PubMed

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