Table 5

Fluorescence in situ hybridisation studies comparing primary breast cancers and their matched distant metastases

Reference
n
Discordance between metastases and primary tumours (percentage)
Number of HER2-positive primary tumours
Number of HER2-positive metastases

[23]
12
0
12
12
[20]
68
7.0
2
3
[22]
14
0
14
14
[21]
18
22.2
3
7
[19]
17
6.0
Not available
Not available
This study
105
7.6
21
20

HER2, gene encoding human EGF-like receptor 2.

Tapia et al. Breast Cancer Research 2007 9:R31   doi:10.1186/bcr1676

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