Table 1

Immunohistochemical analysis of 85 primary breast tumors for pStat3, interleukin-6, estrogen receptor, progesterone receptor, and Her2neu


pStat3 0, 1+ (54%)
pStat3 2, 3+ (46%)
P value (Fisher)

Interleukin-6 (2, 3+)
11
32
0.001
Interleukin-6 (0, 1+)
34
5

Estrogen receptor-positive
21
25
0.20
Estrogen receptor-negative
24
14

Progesterone receptor-positive
16
18
1.0
Progesterone receptor-negative
29
19

Her2neu (2, 3+)
5
7
1.0
Her2neu (0, 1+)
30
25


The correlations between the relationship of pStat3 and interleukin-6, estrogen receptor, progesterone receptor, and Her2neu were measured using the χ2 test. 0 is no staining, 1+ is weak staining, 2+ is moderate staining and 3+ is strong staining for pStat3, tyrosine-phosphorylated signal transducer and activator of transcription 3 and IL-6.

Berishaj et al. Breast Cancer Research 2007 9:R32   doi:10.1186/bcr1680

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