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Molecular response to aromatase inhibitor treatment in primary breast cancer

Alan Mackay* 1 email, Ander Urruticoechea* 2 email, J Michael Dixon4 email, Tim Dexter1 email, Kerry Fenwick1 email, Alan Ashworth1 email, Suzanne Drury2 email, Alexey Larionov3 email, Oliver Young3 email, Sharon White3 email, William R Miller3 email, Dean B Evans4 email and Mitch Dowsett1,2 email

1The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK

2Academic Department of Biochemistry, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK

3The Edinburgh Breast Unit, Western General Hospital, Edinburgh, EH4 2XU, UK

4Novartis Pharma AG, Basel, Switzerland

author email corresponding author email* Contributed equally

Breast Cancer Research 2007, 9:R37doi:10.1186/bcr1732

Published: 7 June 2007

Additional files

Additional file 6:

Annotation of the Breakthrough 17K microarray

Format: XLS Size: 2.9MB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 1:

Primer sequences used in RT-PCR

Format: XLS Size: 12KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 2:

A summary of relevant patient information

Format: XLS Size: 40KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 7:

Java Treeview data for figure 1

Format: CDT Size: 1.2MB Download file

Additional file 8:

Java Treeview data for figure 1

Format: ATR Size: 2KB Download file

Additional file 9:

Java Treeview data for figure 1

Format: GTR Size: 91KB Download file

Additional file 10:

Complete annotation of the genes in the 2418 heatmap

Format: XLS Size: 448KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 3:

A table of individual results used to plot GIDE correlations in figure 2

Format: XLS Size: 15KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 4:

An excel sheet listing all genes significantly up- and downregulated by AI treatment

Format: XLS Size: 2MB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 11:

Java Treeview data for figure 4

Format: CDT Size: 212KB Download file

Additional file 12:

Java Treeview data for figure 4

Format: ATR Size: 2KB Download file

Additional file 13:

Java Treeview data for figure 4

Format: GTR Size: 15KB Download file

Additional file 14:

Complete annotation of the genes in the 421 heatmap

Format: XLS Size: 96KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 5:

An excel sheet listing all genes positively and negatively correlated with ESR1 expression

Format: XLS Size: 133KB Download file

This file can be viewed with: Microsoft Excel Viewer


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