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Molecular response to aromatase inhibitor treatment in primary breast cancer

Alan Mackay1* email, Ander Urruticoechea2* email, J Michael Dixon4 email, Tim Dexter1 email, Kerry Fenwick1 email, Alan Ashworth1 email, Suzanne Drury2 email, Alexey Larionov3 email, Oliver Young3 email, Sharon White3 email, William R Miller3 email, Dean B Evans4 email and Mitch Dowsett1,2 email

1  The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK

2  Academic Department of Biochemistry, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK

3  The Edinburgh Breast Unit, Western General Hospital, Edinburgh, EH4 2XU, UK

4  Novartis Pharma AG, Basel, Switzerland

author email corresponding author email* Contributed equally

Breast Cancer Research 2007, 9:R37doi:10.1186/bcr1732

Published: 7 June 2007

Additional files

Additional file 6:

Annotation of the Breakthrough 17K microarray

Format: XLS Size: 2.8MB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 1:

Primer sequences used in RT-PCR

Format: XLS Size: 12KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 2:

A summary of relevant patient information

Format: XLS Size: 40KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 7:

Java Treeview data for figure 1

Format: CDT Size: 1.2MB Download file

Additional file 8:

Java Treeview data for figure 1

Format: ATR Size: 2KB Download file

Additional file 9:

Java Treeview data for figure 1

Format: GTR Size: 91KB Download file

Additional file 10:

Complete annotation of the genes in the 2418 heatmap

Format: XLS Size: 448KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 3:

A table of individual results used to plot GIDE correlations in figure 2

Format: XLS Size: 15KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 4:

An excel sheet listing all genes significantly up- and downregulated by AI treatment

Format: XLS Size: 1.9MB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 11:

Java Treeview data for figure 4

Format: CDT Size: 212KB Download file

Additional file 12:

Java Treeview data for figure 4

Format: ATR Size: 2KB Download file

Additional file 13:

Java Treeview data for figure 4

Format: GTR Size: 15KB Download file

Additional file 14:

Complete annotation of the genes in the 421 heatmap

Format: XLS Size: 96KB Download file

This file can be viewed with: Microsoft Excel Viewer

Additional file 5:

An excel sheet listing all genes positively and negatively correlated with ESR1 expression

Format: XLS Size: 133KB Download file

This file can be viewed with: Microsoft Excel Viewer

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