Breast Cancer Research

official impact factor 5.79

Open Access Highly Access Research article

Molecular response to aromatase inhibitor treatment in primary breast cancer

Alan Mackay1*, Ander Urruticoechea2, J Michael Dixon4, Tim Dexter1, Kerry Fenwick1, Alan Ashworth1, Suzanne Drury2, Alexey Larionov3, Oliver Young3, Sharon White3, William R Miller3, Dean B Evans4 and Mitch Dowsett1,2

Author Affiliations

1 The Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London, SW3 6JB, UK

2 Academic Department of Biochemistry, Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK

3 The Edinburgh Breast Unit, Western General Hospital, Edinburgh, EH4 2XU, UK

4 Novartis Pharma AG, Basel, Switzerland

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Breast Cancer Research 2007, 9:R37 doi:10.1186/bcr1732

Published: 7 June 2007

Additional files

Additional file 6:

Annotation of the Breakthrough 17K microarray

Format: XLS Size: 2.8MB Download file

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Additional file 1:

Primer sequences used in RT-PCR

Format: XLS Size: 12KB Download file

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Additional file 2:

A summary of relevant patient information

Format: XLS Size: 40KB Download file

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Additional file 7:

Java Treeview data for figure 1

Format: CDT Size: 1.2MB Download file

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Additional file 8:

Java Treeview data for figure 1

Format: ATR Size: 2KB Download file

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Additional file 9:

Java Treeview data for figure 1

Format: GTR Size: 91KB Download file

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Additional file 10:

Complete annotation of the genes in the 2418 heatmap

Format: XLS Size: 448KB Download file

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Additional file 3:

A table of individual results used to plot GIDE correlations in figure 2

Format: XLS Size: 15KB Download file

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Additional file 4:

An excel sheet listing all genes significantly up- and downregulated by AI treatment

Format: XLS Size: 1.9MB Download file

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Additional file 11:

Java Treeview data for figure 4

Format: CDT Size: 212KB Download file

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Additional file 12:

Java Treeview data for figure 4

Format: ATR Size: 2KB Download file

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Additional file 13:

Java Treeview data for figure 4

Format: GTR Size: 15KB Download file

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Additional file 14:

Complete annotation of the genes in the 421 heatmap

Format: XLS Size: 96KB Download file

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Additional file 5:

An excel sheet listing all genes positively and negatively correlated with ESR1 expression

Format: XLS Size: 133KB Download file

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