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Genes upregulated by AI treatment |
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| ID |
Symbol |
Description |
Unigene |
Fold |
LFDR |
|
|
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| HSI022G08 |
LUM |
Lumican |
Hs.406475 |
2.87 |
0.11 |
| HSI101E05 |
ODF2L |
Outer dense fiber of sperm tails 2-like |
Hs.149360 |
2.80 |
0.07 |
| HSI027H04 |
IGJ |
Immunoglobulin J polypeptide |
Hs.381568 |
2.73 |
0.07 |
| HSI082D05 |
RNH1 |
Ribonuclease/angiogenin inhibitor 1 |
Hs.530687 |
2.51 |
0.00 |
| HSI056B04 |
COL3A1 |
Collagen, type III, alpha 1 |
Hs.443625 |
2.50 |
0.00 |
| HSI182D05 |
MRC1L1 |
Mannose receptor, C type 1 |
Hs.461247 |
2.45 |
0.06 |
| HSI067F08 |
C21orf70 |
Chromosome 21 open reading frame 70 |
Hs.410830 |
2.44 |
0.00 |
| HSI127E04 |
CALD1 |
Caldesmon 1 |
Hs.490203 |
2.37 |
0.11 |
| HSI030C06 |
PTPRC |
Protein tyrosine phosphatase, receptor type, C |
Hs.192039 |
2.36 |
0.11 |
| HSI067H02 |
ASPN |
Asporin (LRR class 1) |
Hs.435655 |
2.34 |
0.00 |
| HSI066B08 |
COL14A1 |
Collagen, type XIV, alpha 1 (undulin) |
Hs.409662 |
2.28 |
0.11 |
| HSI049B12 |
COL1A2 |
Collagen, type I, alpha 2 |
Hs.489142 |
2.28 |
0.00 |
| HSI049G07 |
DCN |
Decorin |
Hs.156316 |
2.28 |
0.00 |
| HSI067E05 |
MRC1L1 |
Mannose receptor, C type 1 |
Hs.461247 |
2.22 |
0.05 |
| HSI101D05 |
IFT122 |
Intraflagellar transport 122 homolog (Chlamydomonas) |
Hs.477537 |
2.17 |
0.03 |
| HSI183E05 |
PDGFRA |
Platelet-derived growth factor receptor, alpha |
Hs.74615 |
2.14 |
0.09 |
| HSI031A12 |
FSTL1 |
Follistatin-like 1 |
Hs.269512 |
2.12 |
0.00 |
| HSI183H01 |
COL5A2 |
Collagen, type V, alpha 2 |
Hs.445827 |
2.11 |
0.00 |
| HSI055A11 |
ECM2 |
Extracellular matrix protein 2 |
Hs.117060 |
2.08 |
0.09 |
| HSI018G02 |
SPON1 |
Spondin 1, extracellular matrix protein |
Hs.445818 |
2.06 |
0.00 |
| HSI183B01 |
PDGFRA |
Platelet-derived growth factor receptor, alpha |
Hs.74615 |
2.04 |
0.01 |
| HSI037C02 |
CPVL |
Carboxypeptidase, vitellogenic-like |
Hs.233389 |
2.03 |
0.06 |
| HSI062B08 |
SAS10 |
Disrupter of silencing 10 |
Hs.322901 |
2.01 |
0.00 |
| HSI129E10 |
ADAM12 |
ADAM metallopeptidase domain 12 (meltrin alpha) |
Hs.386283 |
2.00 |
0.00 |
| HSI183G08 |
RGS1 |
Regulator of G-protein signalling 1 |
Hs.75256 |
1.98 |
0.18 |
| HSI054F01 |
VIM |
Vimentin |
Hs.533317 |
1.97 |
0.00 |
| HSI048C08 |
CTGF |
Connective tissue growth factor |
Hs.410037 |
1.97 |
0.00 |
| HSI183G05 |
SPARC |
Secreted protein, acidic, cysteine-rich (osteonectin) |
Hs.111779 |
1.96 |
0.00 |
| HSI139G09 |
ADAMTS2 |
ADAM metallopeptidase with thrombospondin motif 2 |
Hs.23871 |
1.96 |
0.00 |
| HSI018D05 |
FBLN1 |
Fibulin 1 |
Hs.24601 |
1.95 |
0.00 |
| HSI040E08 |
DUSP1 |
Dual specificity phosphatase 1 |
Hs.171695 |
1.95 |
0.00 |
| HSI082C05 |
MAN1A1 |
Mannosidase, alpha, class 1A, member 1 |
Hs.102788 |
1.94 |
0.01 |
| HSI098G12 |
RARRES1 |
Retinoic acid receptor responder 1 |
Hs.131269 |
1.94 |
0.00 |
| HSI044C09 |
SAT |
Spermidine/spermine N1-acetyltransferase |
Hs.28491 |
1.92 |
0.09 |
| HSI030F05 |
HTRA1 |
HtrA serine peptidase 1 |
Hs.501280 |
1.92 |
0.00 |
| HSI088D11 |
CILP |
Cartilage intermediate layer protein |
Hs.442180 |
1.91 |
0.00 |
| HSI040E09 |
MME |
Membrane metallo-endopeptidase (CALLA, CD10) |
Hs.307734 |
1.91 |
0.00 |
| HSI028G12 |
PDGFRA |
Platelet-derived growth factor receptor, alpha |
Hs.74615 |
1.89 |
0.00 |
| HSI060C05 |
FN1 |
Fibronectin 1 |
Hs.203717 |
1.89 |
0.00 |
| HSI045G12 |
CXCL12 |
Chemokine ligand 12 (stromal cell-derived factor 1) |
Hs.522891 |
1.88 |
0.00 |
|
Shown are the first 40 upregulated genes from a paired SAM analysis, which identified 1,365 genes to be upregulated by aromatase inhibitor (AI) treatment below a local false discovery rate of 1% (LFDR). The genes are ranked according to their fold change. | |||||
Mackay et al. Breast Cancer Research 2007 9:R37 doi:10.1186/bcr1732 |
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