Figure 2.

Network of functional association between TNF gene and other GATMs generated by Ingenuity database analysis. RAET1B, KLRD1 and KLRK1 are genes associated with cytotoxicity; TNFRSF21 and AATK are genes involved in apoptosis. LITAF, AK2 and KLRC2 are genes associated with proliferation regulation. PLA2G7 is a gene associated with inflammatory response. All of the other genes have unknown cell functions. Genes are shown by their symbols [44]. The nodes represent the genes and the edges reflect direct links or connections between them. GATM, gene associated with mammary tumour microenvironment; TNF, tumour necrosis factor.