Table 2 |
||||||
|
The effect of chemotherapy agents on tracer uptake after 3-day treatment |
||||||
|
Treatment |
Dose (μM) |
% PET Tracer uptake reduction |
||||
|
|
||||||
|
FLT |
FDG |
CHO |
MET |
ACE |
||
|
|
||||||
|
Paclitaxel |
1 |
68 ± 7 |
21 ± 8 |
-13 ± 9 |
6 ± 7 |
-10 ± 7 |
|
10 |
69 ± 7 |
17 ± 7 |
-6 ± 9 |
7 ± 7 |
-10 ± 8 |
|
|
Docetaxel |
1 |
66 ± 6 |
27 ± 7 |
-3 ± 7 |
13 ± 6 |
1 ± 5 |
|
10 |
66 ± 6 |
27 ± 6 |
-2 ± 7 |
1 ± 6 |
-7 ± 5 |
|
|
Doxorubicin |
1 |
76 ± 5 |
18 ± 5 |
5 ± 6 |
-8 ± 5 |
14 ± 5 |
|
10 |
95 ± 6 |
71 ± 6 |
27 ± 8 |
38 ± 9 |
48 ± 7 |
|
|
Tamoxifen |
1 |
11± 8 |
2 ± 9 |
-2 ± 9 |
0 ± 7 |
-7 ± 7 |
|
10 |
28 ± 7 |
22 ± 8 |
-2 ± 9 |
-7 ± 7 |
-45 ± 7 |
|
|
Imatinib |
1 |
7 ± 7 |
3 ± 9 |
4 ± 9 |
-6 ± 7 |
2 ± 7 |
|
|
||||||
|
Monazzam et al. Breast Cancer Research 2007 9:R45 doi:10.1186/bcr1747 |
||||||
