Breast Cancer Research | Volume 9 Issue 6

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	Volume 9 Issue 6
	Comment
	Commentary Genes harbouring susceptibility SNPs are differentially expressed in the breast cancer subtypes Silje H Nordgard, Fredrik E Johansen, Grethe IG Alnæs, Bjørn Naume, Anne-Lise Børresen-Dale, Vessela N Kristensen Breast Cancer Research 2007, 9:113 (19 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary The promise and limitations of genome-wide association studies to elucidate the causes of breast cancer Christine B Ambrosone Breast Cancer Research 2007, 9:114 (5 December 2007) Abstract \| Full text \| PDF \| PubMed
	Commentary Adjuvant endocrine therapy for premenopausal women with early breast cancer Ting Bao, Nancy E Davidson Breast Cancer Research 2007, 9:115 (17 December 2007) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Genomics and premalignant breast lesions: clues to the development and progression of lobular breast cancer Teresa L Mastracci, Fouad I Boulos, Irene L Andrulis, Wan L Lam Breast Cancer Research 2007, 9:215 (16 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Breast tumour angiogenesis Stephen B Fox, Daniele G Generali, Adrian L Harris Breast Cancer Research 2007, 9:216 (18 December 2007) Abstract \| Full text \| PDF \| PubMed
	Review Mammographic density, breast cancer risk and risk prediction Celine M Vachon, Carla H van Gils, Thomas A Sellers, Karthik Ghosh, Sandhya Pruthi, Kathleen R Brandt, V Shane Pankratz Breast Cancer Research 2007, 9:217 (20 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Report
	Correction Correction: Decline in breast cancer incidence due to removal of promoter: combination estrogen plus progestin Graham A Colditz Breast Cancer Research 2007, 9:401 (15 November 2007) Full text \| PDF \| PubMed
	Research
	Research article Serum epidermal growth factor receptor and HER2 expression in primary and metastatic breast cancer patients Kristjan S Asgeirsson, Amit Agrawal, Claire Allen, Anthony Hitch, Ian O Ellis, Caroline Chapman, Kwok L Cheung, John FR Robertson Breast Cancer Research 2007, 9:R75 (1 November 2007) Abstract \| Full text \| PDF \| PubMed
	Research article Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer Xin-Zhong Chang, Da-Qiang Li, Yi-Feng Hou, Jiong Wu, Jin-Song Lu, Gen-Hong Di, Wei Jin, Zhou-Luo Ou, Zhen-Zhou Shen, Zhi-Ming Shao Breast Cancer Research 2007, 9:R76 (2 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells Cheng Jiang, Junming Guo, Zhe Wang, Bingxiu Xiao, Hyo-Jung Lee, Eun-Ok Lee, Sung-Hoon Kim, Junxuan Lu Breast Cancer Research 2007, 9:R77 (6 November 2007) Abstract \| Full text \| PDF \| PubMed
	Research article Clinical correlates of low-risk variants in FGFR2, TNRC9, MAP3K1, LSP1 and 8q24 in a Dutch cohort of incident breast cancer cases Petra EA Huijts, Maaike PG Vreeswijk, Karin HG Kroeze-Jansema, Catharina E Jacobi, Caroline Seynaeve, Elly MM Krol-Warmerdam, Pauline M Wijers-Koster, Jannet C Blom, Karen A Pooley, Jan GM Klijn, Rob AEM Tollenaar, Peter Devilee, Christi J van Asperen Breast Cancer Research 2007, 9:R78 (12 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Recently discovered genomic variants associated with a mildly increased risk of breast cancer are also associated with clinical characteristics or family history of breast and ovarian cancer.
	Research article Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6 Amanda M Weaver, Corinne M Silva Breast Cancer Research 2007, 9:R79 (12 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Breast tumour kinase (Brk) signals downstream to a key regulator of tumourigenesis to mediate proliferation of breast cancer cells, making it a potential target for breast cancer therapy.
	Research article Inhibition of proteasome activity by the dietary flavonoid apigenin is associated with growth inhibition in cultured breast cancer cells and xenografts Di Chen, Kristin R Landis-Piwowar, Marina S Chen, Q Ping Dou Breast Cancer Research 2007, 9:R80 (21 November 2007) Abstract \| Full text \| PDF \| PubMed
	Research article International Web-based consultation on priorities for translational breast cancer research Mitch Dowsett, Aron Goldhirsch, Daniel F Hayes, Hans-Joerg Senn, William Wood, Giuseppe Viale Breast Cancer Research 2007, 9:R81 (22 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A group of more than 400 experts have identified the top priorities for translational breast cancer research, potentially focusing resources onto the issues identified in this web-based consultation.
	Research article Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants? Paul K Lovelock, Amanda B Spurdle, Myth TS Mok, Daniel J Farrugia, Sunil R Lakhani, Sue Healey, Stephen Arnold, Daniel Buchanan, kConFab Investigators, Fergus J Couch, Beric R Henderson, David E Goldgar, Sean V Tavtigian, Georgia Chenevix-Trench, Melissa A Brown Breast Cancer Research 2007, 9:R82 (26 November 2007) Abstract \| Full text \| PDF \| PubMed
	Research article Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women William D Foulkes, Parviz Ghadirian, Mohammed Akbari, Nancy Hamel, Sylvie Giroux, Nelly Sabbaghian, Andrew Darnel, Robert Royer, Aletta Poll, Eve Fafard, André Robidoux, Ginette Martin, Tarek A Bismar, Marc Tischkowitz, Francois Rousseau, Steven A Narod Breast Cancer Research 2007, 9:R83 (3 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case-control study of Caucasian and African-American women Britton Trabert, Kathleen E Malone, Janet R Daling, David R Doody, Leslie Bernstein, Giske Ursin, Polly A Marchbanks, Brian L Strom, Mariela C Humphrey, Elaine A Ostrander Breast Cancer Research 2007, 9:R84 (7 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Polymorphisms of the vitamin D receptor gene are associated with an increased breast cancer risk in postmenopausal Caucasian women, a large population-based, case-control study has found.
	Research article Regulator of G-protein signalling 2 mRNA is differentially expressed in mammary epithelial subpopulations and over-expressed in the majority of breast cancers Matthew J Smalley, Marjan Iravani, Maria Leao, Anita Grigoriadis, Howard Kendrick, Tim Dexter, Kerry Fenwick, Joseph L Regan, Kara Britt, Sarah McDonald, Christopher J Lord, Alan MacKay, Alan Ashworth Breast Cancer Research 2007, 9:R85 (8 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity Maximino Redondo, Teresa Téllez, Maria J Roldan, Alfonso Serrano, Maria García-Aranda, Martin E Gleave, Maria L Hortas, Miguel Morell Breast Cancer Research 2007, 9:R86 (13 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Anticlusterin treatment combined with routine anticancer drugs used in breast cancer therapy may inhibit the progression of breast cancer by regulation of the clusterin function.
	Research article CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer Francisco J Esteva, Jing Wang, Feng Lin, Jaime A Mejia, Kai Yan, Kadri Altundag, Vicente Valero, Aman U Buzdar, Gabriel N Hortobagyi, W Fraser Symmans, Lajos Pusztai Breast Cancer Research 2007, 9:R87 (17 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Research article A prospective pilot clinical trial evaluating the utility of a dynamic near-infrared imaging device for characterizing suspicious breast lesions Ronald X Xu, Donn C Young, Jimmy J Mao, Stephen P Povoski Breast Cancer Research 2007, 9:R88 (18 December 2007) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Dynamic near infra red imaging, a portable, noninvasive technique, has the potential to differentiate between benign processes and malignant tumours in suspicious breast lesions.
	Research article Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer Ern Tan, Leticia Campo, Cheng Han, Helen Turley, Francesco Pezzella, Kevin C Gatter, Adrian L Harris, Stephen B Fox Breast Cancer Research 2007, 9:R89 (20 December 2007) Abstract \| Full text \| PDF \| PubMed
	Research article Recent breast cancer trends among Asian/Pacific Islander, Hispanic, and African-American women in the US: changes by tumor subtype Amelia K Hausauer, Theresa HM Keegan, Ellen T Chang, Christina A Clarke Breast Cancer Research 2007, 9:R90 (27 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Multi-ethnic population-based trends provide further evidence that hormone therapy use has a major influence on rates of breast cancer subtypes and particularly on the number of estrogen-positive tumours.
	Research article Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-α mice Soner Dogan, Xin Hu, Yan Zhang, Nita J Maihle, Joseph P Grande, Margot P Cleary Breast Cancer Research 2007, 9:R91 (27 December 2007) Abstract \| Full text \| PDF \| PubMed
	Correspondence
	Letter The protective side of progesterone Gianluigi Ferretti, Alessandra Felici, Francesco Cognetti Breast Cancer Research 2007, 9:402 (21 November 2007) Abstract \| Full text \| PDF \| PubMed
	Letter Osteoactivin/HGFIN: is it a tumor suppressor or mediator of metastasis in breast cancer? April AN Rose, Peter M Siegel Breast Cancer Research 2007, 9:403 (27 November 2007) Abstract \| Full text \| PDF \| PubMed
	Letter Are triple-negative tumours and basal-like breast cancer synonymous? Authors' response Bas Kreike, Marc J van de Vijver Breast Cancer Research 2007, 9:405 (17 December 2007) Abstract \| Full text \| PDF \| PubMed
	Letter Are triple-negative tumours and basal-like breast cancer synonymous? Emad A Rakha, David SP Tan, William D Foulkes, Ian O Ellis, Andrew Tutt, Torsten O Nielsen, Jorge S Reis-Filho Breast Cancer Research 2007, 9:404 (30 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

	Volume 9 Issue 6
	Comment
	Commentary Genes harbouring susceptibility SNPs are differentially expressed in the breast cancer subtypes Silje H Nordgard, Fredrik E Johansen, Grethe IG Alnæs, Bjørn Naume, Anne-Lise Børresen-Dale, Vessela N Kristensen Breast Cancer Research 2007, 9:113 (19 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary The promise and limitations of genome-wide association studies to elucidate the causes of breast cancer Christine B Ambrosone Breast Cancer Research 2007, 9:114 (5 December 2007) Abstract \| Full text \| PDF \| PubMed
	Commentary Adjuvant endocrine therapy for premenopausal women with early breast cancer Ting Bao, Nancy E Davidson Breast Cancer Research 2007, 9:115 (17 December 2007) Abstract \| Full text \| PDF \| PubMed
	Review
	Review Genomics and premalignant breast lesions: clues to the development and progression of lobular breast cancer Teresa L Mastracci, Fouad I Boulos, Irene L Andrulis, Wan L Lam Breast Cancer Research 2007, 9:215 (16 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Breast tumour angiogenesis Stephen B Fox, Daniele G Generali, Adrian L Harris Breast Cancer Research 2007, 9:216 (18 December 2007) Abstract \| Full text \| PDF \| PubMed
	Review Mammographic density, breast cancer risk and risk prediction Celine M Vachon, Carla H van Gils, Thomas A Sellers, Karthik Ghosh, Sandhya Pruthi, Kathleen R Brandt, V Shane Pankratz Breast Cancer Research 2007, 9:217 (20 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Report
	Correction Correction: Decline in breast cancer incidence due to removal of promoter: combination estrogen plus progestin Graham A Colditz Breast Cancer Research 2007, 9:401 (15 November 2007) Full text \| PDF \| PubMed
	Research
	Research article Serum epidermal growth factor receptor and HER2 expression in primary and metastatic breast cancer patients Kristjan S Asgeirsson, Amit Agrawal, Claire Allen, Anthony Hitch, Ian O Ellis, Caroline Chapman, Kwok L Cheung, John FR Robertson Breast Cancer Research 2007, 9:R75 (1 November 2007) Abstract \| Full text \| PDF \| PubMed
	Research article Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer Xin-Zhong Chang, Da-Qiang Li, Yi-Feng Hou, Jiong Wu, Jin-Song Lu, Gen-Hong Di, Wei Jin, Zhou-Luo Ou, Zhen-Zhou Shen, Zhi-Ming Shao Breast Cancer Research 2007, 9:R76 (2 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Decursin and decursinol angelate inhibit estrogen-stimulated and estrogen-independent growth and survival of breast cancer cells Cheng Jiang, Junming Guo, Zhe Wang, Bingxiu Xiao, Hyo-Jung Lee, Eun-Ok Lee, Sung-Hoon Kim, Junxuan Lu Breast Cancer Research 2007, 9:R77 (6 November 2007) Abstract \| Full text \| PDF \| PubMed
	Research article Clinical correlates of low-risk variants in FGFR2, TNRC9, MAP3K1, LSP1 and 8q24 in a Dutch cohort of incident breast cancer cases Petra EA Huijts, Maaike PG Vreeswijk, Karin HG Kroeze-Jansema, Catharina E Jacobi, Caroline Seynaeve, Elly MM Krol-Warmerdam, Pauline M Wijers-Koster, Jannet C Blom, Karen A Pooley, Jan GM Klijn, Rob AEM Tollenaar, Peter Devilee, Christi J van Asperen Breast Cancer Research 2007, 9:R78 (12 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Recently discovered genomic variants associated with a mildly increased risk of breast cancer are also associated with clinical characteristics or family history of breast and ovarian cancer.
	Research article Signal transducer and activator of transcription 5b: a new target of breast tumor kinase/protein tyrosine kinase 6 Amanda M Weaver, Corinne M Silva Breast Cancer Research 2007, 9:R79 (12 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Breast tumour kinase (Brk) signals downstream to a key regulator of tumourigenesis to mediate proliferation of breast cancer cells, making it a potential target for breast cancer therapy.
	Research article Inhibition of proteasome activity by the dietary flavonoid apigenin is associated with growth inhibition in cultured breast cancer cells and xenografts Di Chen, Kristin R Landis-Piwowar, Marina S Chen, Q Ping Dou Breast Cancer Research 2007, 9:R80 (21 November 2007) Abstract \| Full text \| PDF \| PubMed
	Research article International Web-based consultation on priorities for translational breast cancer research Mitch Dowsett, Aron Goldhirsch, Daniel F Hayes, Hans-Joerg Senn, William Wood, Giuseppe Viale Breast Cancer Research 2007, 9:R81 (22 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary A group of more than 400 experts have identified the top priorities for translational breast cancer research, potentially focusing resources onto the issues identified in this web-based consultation.
	Research article Identification of BRCA1 missense substitutions that confer partial functional activity: potential moderate risk variants? Paul K Lovelock, Amanda B Spurdle, Myth TS Mok, Daniel J Farrugia, Sunil R Lakhani, Sue Healey, Stephen Arnold, Daniel Buchanan, kConFab Investigators, Fergus J Couch, Beric R Henderson, David E Goldgar, Sean V Tavtigian, Georgia Chenevix-Trench, Melissa A Brown Breast Cancer Research 2007, 9:R82 (26 November 2007) Abstract \| Full text \| PDF \| PubMed
	Research article Identification of a novel truncating PALB2 mutation and analysis of its contribution to early-onset breast cancer in French-Canadian women William D Foulkes, Parviz Ghadirian, Mohammed Akbari, Nancy Hamel, Sylvie Giroux, Nelly Sabbaghian, Andrew Darnel, Robert Royer, Aletta Poll, Eve Fafard, André Robidoux, Ginette Martin, Tarek A Bismar, Marc Tischkowitz, Francois Rousseau, Steven A Narod Breast Cancer Research 2007, 9:R83 (3 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case-control study of Caucasian and African-American women Britton Trabert, Kathleen E Malone, Janet R Daling, David R Doody, Leslie Bernstein, Giske Ursin, Polly A Marchbanks, Brian L Strom, Mariela C Humphrey, Elaine A Ostrander Breast Cancer Research 2007, 9:R84 (7 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Polymorphisms of the vitamin D receptor gene are associated with an increased breast cancer risk in postmenopausal Caucasian women, a large population-based, case-control study has found.
	Research article Regulator of G-protein signalling 2 mRNA is differentially expressed in mammary epithelial subpopulations and over-expressed in the majority of breast cancers Matthew J Smalley, Marjan Iravani, Maria Leao, Anita Grigoriadis, Howard Kendrick, Tim Dexter, Kerry Fenwick, Joseph L Regan, Kara Britt, Sarah McDonald, Christopher J Lord, Alan MacKay, Alan Ashworth Breast Cancer Research 2007, 9:R85 (8 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity Maximino Redondo, Teresa Téllez, Maria J Roldan, Alfonso Serrano, Maria García-Aranda, Martin E Gleave, Maria L Hortas, Miguel Morell Breast Cancer Research 2007, 9:R86 (13 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Anticlusterin treatment combined with routine anticancer drugs used in breast cancer therapy may inhibit the progression of breast cancer by regulation of the clusterin function.
	Research article CD40 signaling predicts response to preoperative trastuzumab and concomitant paclitaxel followed by 5-fluorouracil, epirubicin, and cyclophosphamide in HER-2-overexpressing breast cancer Francisco J Esteva, Jing Wang, Feng Lin, Jaime A Mejia, Kai Yan, Kadri Altundag, Vicente Valero, Aman U Buzdar, Gabriel N Hortobagyi, W Fraser Symmans, Lajos Pusztai Breast Cancer Research 2007, 9:R87 (17 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| 1 comment
	Research article A prospective pilot clinical trial evaluating the utility of a dynamic near-infrared imaging device for characterizing suspicious breast lesions Ronald X Xu, Donn C Young, Jimmy J Mao, Stephen P Povoski Breast Cancer Research 2007, 9:R88 (18 December 2007) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Dynamic near infra red imaging, a portable, noninvasive technique, has the potential to differentiate between benign processes and malignant tumours in suspicious breast lesions.
	Research article Cytoplasmic location of factor-inhibiting hypoxia-inducible factor is associated with an enhanced hypoxic response and a shorter survival in invasive breast cancer Ern Tan, Leticia Campo, Cheng Han, Helen Turley, Francesco Pezzella, Kevin C Gatter, Adrian L Harris, Stephen B Fox Breast Cancer Research 2007, 9:R89 (20 December 2007) Abstract \| Full text \| PDF \| PubMed
	Research article Recent breast cancer trends among Asian/Pacific Islander, Hispanic, and African-American women in the US: changes by tumor subtype Amelia K Hausauer, Theresa HM Keegan, Ellen T Chang, Christina A Clarke Breast Cancer Research 2007, 9:R90 (27 December 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Multi-ethnic population-based trends provide further evidence that hormone therapy use has a major influence on rates of breast cancer subtypes and particularly on the number of estrogen-positive tumours.
	Research article Effects of high-fat diet and/or body weight on mammary tumor leptin and apoptosis signaling pathways in MMTV-TGF-α mice Soner Dogan, Xin Hu, Yan Zhang, Nita J Maihle, Joseph P Grande, Margot P Cleary Breast Cancer Research 2007, 9:R91 (27 December 2007) Abstract \| Full text \| PDF \| PubMed
	Correspondence
	Letter The protective side of progesterone Gianluigi Ferretti, Alessandra Felici, Francesco Cognetti Breast Cancer Research 2007, 9:402 (21 November 2007) Abstract \| Full text \| PDF \| PubMed
	Letter Osteoactivin/HGFIN: is it a tumor suppressor or mediator of metastasis in breast cancer? April AN Rose, Peter M Siegel Breast Cancer Research 2007, 9:403 (27 November 2007) Abstract \| Full text \| PDF \| PubMed
	Letter Are triple-negative tumours and basal-like breast cancer synonymous? Authors' response Bas Kreike, Marc J van de Vijver Breast Cancer Research 2007, 9:405 (17 December 2007) Abstract \| Full text \| PDF \| PubMed
	Letter Are triple-negative tumours and basal-like breast cancer synonymous? Emad A Rakha, David SP Tan, William D Foulkes, Ian O Ellis, Andrew Tutt, Torsten O Nielsen, Jorge S Reis-Filho Breast Cancer Research 2007, 9:404 (30 November 2007) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

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Volume 9 Issue 6

Comment

Review

Report

Research

Correspondence