Breast Cancer Research

official impact factor 5.79

Letter

Are triple-negative tumours and basal-like breast cancer synonymous? Authors' response

Bas Kreike1,2 and Marc J van de Vijver3*

Author Affiliations

1 Division of Radiation Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

2 Division of Experimental Therapy, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

3 Division of Diagnostic Oncology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

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Breast Cancer Research 2007, 9:405 doi:10.1186/bcr1832

Published: 17 December 2007

First paragraph (this article has no abstract)

We read with interest the issues raised by Rakha and colleagues [1] in their response to our recent research article [2], and we are pleased to address them. An important conclusion from our research article is that triple-negative breast cancer can be equated to basal-like breast cancer. In their letter, Rakha and colleagues [1] state that equating triple-negative phenotype (TNP) tumours with basal-like breast cancer is misleading and is not supported by the data we have presented.