Table 1 |
|
|
Baseline characteristics of the Dutch hospital-based ORIGO cohort of breast cancer patients (n = 1267) |
|
| Variable |
Value |
|
|
|
| Age at diagnosis (years) (n = 1,254) |
54 ± 11.2 (21–88) |
| Follow-up time (months) (n = 476) |
64 ± 31 (3–126) |
| Body mass index (kg/m2) (n = 1,203) |
25 ± 4 (16–45) |
| Sex (n = 1,267) |
|
| Female |
1262 (99.6%) |
| Male |
5 (0.4%) |
| Bilaterality of breast cancera (n = 1,265) |
|
| Bilateral |
79 (6.2%) |
| Unilateral |
1186 (93.8%) |
| Tumour characteristics |
|
| Bloom–Richardson grade (n = 964) |
|
| Grade I |
175 (18.2%) |
| Grade II |
399 (41.4%) |
| Grade III |
390 (40.5%) |
| Clinical staging of cancer (UICC)b (n = 1,230) |
|
| Stage 0 (in situ) |
144 (11.7%) |
| Stage 1 |
479 (38.9%) |
| Stage 2 |
526 (42.8%) |
| Stage 3 |
81 (6.6%) |
| Receptor status |
|
| Oestrogen receptor (n = 831) |
|
| Positive |
597 (71.8%) |
| Negative |
234 (28.2%) |
| Progesterone receptor (n = 683) |
|
| Positive |
399 (58.4%) |
| Negative |
284 (41.6%) |
| Human epidermal growth factor receptor 2 (HER2/neu) (n = 76) |
|
| Positive |
14 (18.4%) |
| Negative |
62 (81.6%) |
| Risk factors |
|
| Family historyc (n = 1,253) |
|
| Negative |
753 (60.1%) |
| Positive |
500 (39.9%) |
| Pregnancy (n = 1,179) |
|
| Ever |
968 (82.1%) |
| Never |
211 (17.9%) |
| Breastfeeding (n = 1,215) |
|
| Ever |
693 (57%) |
| Never |
522 (43%) |
| Breastfeeding duration (months) |
5.21 ± 9.8 (0–121) |
|
|
|
|
Data presented as the mean ± standard deviation (range) or number (% of total number). aWithin 6 months of first diagnosis. bInternational Union Against Cancer (UICC) stages, based on T classification and N classification, known in 1,230 patients. cFamily history is considered positive when at least one first-degree or second-degree relative also had breast cancer, irrespective of age at onset. |
|
|
Huijts et al. Breast Cancer Research 2007 9:R78 doi:10.1186/bcr1793 |
|
