Breast Cancer Research

official impact factor 5.79

Open Access Highly Access Research article

Regulator of G-protein signalling 2 mRNA is differentially expressed in mammary epithelial subpopulations and over-expressed in the majority of breast cancers

Matthew J Smalley1*, Marjan Iravani1, Maria Leao1,2, Anita Grigoriadis1,2, Howard Kendrick1, Tim Dexter1, Kerry Fenwick1, Joseph L Regan1, Kara Britt1, Sarah McDonald1, Christopher J Lord1, Alan MacKay1 and Alan Ashworth1

Author Affiliations

1 Breakthrough Breast Cancer Research Centre, The Institute of Cancer Research, Fulham Road, London SW3 6JB, UK

2 The Ludwig Institute for Cancer Research, Riding House Street, London W1W 7BS, UK

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Breast Cancer Research 2007, 9:R85 doi:10.1186/bcr1834

Published: 8 December 2007

Additional files

Additional file 1:

An .XLS file showing the results of cDNA microarray analysis of Sca-1+/33A10Low/- mammary cells with reference population. Genes are ranked by their M ratio. Only well annotated genes with a significant P value (<0.05) are shown. SOURCE Clone ID [54], UniGene ID, gene name and gene symbol are also given for each gene.

Format: XLS Size: 38KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 2:

An .XLS file showing the results of cDNA microarray analysis of Sca-1-/33A10High mammary cells with reference population. Genes are ranked by their M ratio. Only well annotated genes with a significant P value (<0.05) are shown. SOURCE Clone ID [54], UniGene ID, gene name and gene symbol are also given for each gene.

Format: XLS Size: 30KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 3:

An .XLS file showing the results of cDNA microarray analysis of Sca-1-/33A10Low/- mammary cells with reference population. Genes are ranked by their M ratio. Only well annotated genes with a significant P value (<0.05) are shown. SOURCE Clone ID [54], UniGene ID, gene name and gene symbol are also given for each gene.

Format: XLS Size: 46KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 4:

An .XLS file showing the results of cDNA microarray analysis of mammary fibroblasts with reference population. Genes are ranked by their M ratio. Only well annotated genes with a significant P value (<0.05) are shown. SOURCE Clone ID [54], UniGene ID, gene name and gene symbol are also given for each gene.

Format: XLS Size: 67KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 5:

An .XLS file showing the comparison of cDNA microarray data of all significant genes across all cell populations. Genes are listed alphabetically and their M ratio and P value (<0.05) for each cell population are shown. SOURCE Clone ID [54], UniGene ID, gene name and gene symbol are also given for each gene.

Format: XLS Size: 108KB Download file

This file can be viewed with: Microsoft Excel Viewer

Open Data

Additional file 6:

A .TIFF file showing the Gene Ontology biological process analysis of microarray data. Presented is a graphical representation of percentages of genes involved in differing biological processes, as defined by Gene Ontology annotation, for each cell population.

Format: TIFF Size: 1.1MB Download file

Open Data