It's all in the details: methods in breast development and cancer

doi:10.1186/bcr2346

Breast Cancer Research

Volume 11
Issue 4

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Bentires-Alj M
Clarke RB
Jonkers J
Smalley M
Stein T

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Clarke RB
Jonkers J
Smalley M
Stein T
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Meeting report

It's all in the details: methods in breast development and cancer

Mohamed Bentires-Alj¹ , Robert B Clarke² , Jos Jonkers³ , Matthew Smalley⁴ and Torsten Stein⁵

¹Friedrich Miescher Institute for Biomedical Research (FMI), Maulbeerstr. 66; CH-4058 Basel, Switzerland

²Breast Biology Group School of Cancer and Imaging Sciences, Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK

³Netherlands Cancer Institute; Division of Molecular Biology (P2), Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands

⁴Breakthrough Breast Cancer Centre, Institute of Cancer Research, 237 Fulham Road, London SW3 6JB, UK

⁵Division of Cancer Sciences and Molecular Pathology, Section of Pathology and Gene Regulation, Western Infirmary, University of Glasgow, Glasgow G11 6NT, UK

author email corresponding author email

Breast Cancer Research 2009, 11:305doi:10.1186/bcr2346


Published:	14 August 2009

Abstract

The inaugural European Network for Breast Development and Cancer (ENBDC) meeting on 'Methods in Mammary Gland Development and Cancer' was held in Weggis, Switzerland last April. The goal was to discuss the details of techniques used to study mammary gland biology and tumourigenesis. Highlights of this meeting included the use of four-colour fluorescence for protein co-localisation in tissue microarrays, genome analysis at single cell resolution, technical issues in the isolation of normal and tumour stem cells, and the use of mouse models and mammary gland transplantations to elucidate gene function in mammary development and to study drug resistance in breast cancer.