Is the Mammotome excision of indeterminate impalpable lesions found incidentally on mammography best practice?

bcr1425 BCJ Oral Presentation Is the Mammotome excision of indeterminate impalpable lesions found incidentally on mammography best practice? Lawson S Hubbard A

Humberside Breast Screening Service, Cottingham, UK

Breast Cancer Research Symposium Mammographicum 2006 Meeting abstracts http://breast-cancer-research.com/content/pdf/bcr1425.pdf Symposium Mammographicum 2006 Bournemouth, UK

9–11 July 2006

http://www.sympmamm.org.uk/ 1465-5411 2006 8 Suppl 1 P10 10.1186/bcr1425 10 7 2006

Mammotome excision of indeterminate (B3) impalpable lesions combined with annual mammographic follow-up can be regarded as routine practice.

This quantitative study retrospectively reviewed consecutive Mammotome procedures from January 2003 to July 2005. B3 outcomes were analysed by category combined with follow-up for any evidence of histological upgrade to carcinoma.

Out of a total of 120 consecutive Mammotome procedures, 61 (58%) had a B3 outcome. The B3 category subdivided into: 37% (n = 23) atypical ductal hyperplasia, 37% (n = 23) as radial scars, with the remaining 26% (n = 15) in a mixed category containing mucoceles, lobular carcinoma in situ, and papillomata. A total of 42.6% (n = 26) of the B3 category underwent annual mammographic follow-up with no signs of recurrence, 41% (n = 25) proceeded to 3-yearly NHSBSP routine recall follow-up, and 9.8% (n = 6) proceeded to surgical follow-up with two patients being up-graded to carcinoma. Four patients were lost to follow-up. The incidence of carcinoma in the B3 category ranged between 3.6% and 6.3%.

Trends demonstrated that Mammotome excision for B3 lesions combined with annual mammographic follow-up can be safe practice providing each case is discussed within a multidisciplinary setting with regard to atypia, past history and concordance of imaging and results.