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<art>
   <ui>bcr205</ui>
   <ji>BCJ</ji>
   <fm>
      <dochead>Meeting abstract</dochead>
      <bibl>
         <title>
            <p>Preliminary results of a pilot study into the diagnostic value of T scan in detecting breast malignancies</p>
         </title>
         <aug>
            <au id="A1">
               <snm>Tetlow</snm>
               <fnm>RL</fnm>
               <insr iid="I1"/>
            </au>
            <au id="A2">
               <snm>Hubbard</snm>
               <fnm>AE</fnm>
               <insr iid="I1"/>
            </au>
         </aug>
         <insg>
            <ins id="I1">
               <p>Humberside Breast Screening Unit, Hull and East Yorkshire Hospitals NHS Trust, Kingston upon Hull, UK</p>
            </ins>
         </insg>
         <source>Breast Cancer Res</source>
         <supplement>
            <title>
               <p>Symposium Mammographicum 2000</p>
            </title>
            <note>Meeting abstracts</note>
         </supplement>
         <conference>
            <title>
               <p>Symposium Mammographicum 2000</p>
            </title>
            <location>York, UK</location>
            <date-range>4&#8211;6 October 2000</date-range>
         </conference>
         <issn>1465-5411</issn>
         <pubdate>2000</pubdate>
         <volume>2</volume>
         <issue>Suppl 2</issue>
         <fpage>A13</fpage>
         <xrefbib>
            <pubid idtype="doi">10.1186/bcr205</pubid>
         </xrefbib>
      </bibl>
      <history>
         <pub>
            <date>
               <day>4</day>
               <month>10</month>
               <year>2000</year>
            </date>
         </pub>
      </history>
      <cpyrt>
         <year>2000</year>
         <collab>Current Science Ltd</collab>
      </cpyrt>
   </fm>
   <meta>
      <classifications>
         <classification type="BMC" subtype="old_arx_id">bcr-2-s2-13</classification>
      </classifications>
   </meta>
   <bdy>
      <sec>
         <st>
            <p>Full text</p>
         </st>
         <p>Research into the electrical impedance of tissues has demonstrated a spread of dielectric data from tumour tissue, suggesting structural inhomogeneities. Correlations have been found that may aid in the detection of breast carcinoma. The T scan measures these changes. This study reports on the results, when used in a clinical setting.</p>
         <p>Twenty-seven women, mean age 50 years, referred from a symptomatic clinic, volunteered to have additional T scanning. The results from all imaging modalities were compared and correlated with cytology or histology.</p>
         <p>Patients under 35 years old did not have mammography; all patients had ultrasound. The T scan agreed with the other imaging modalities in 18 cases, giving a bright signal in malignancy and no signal when there was no abnormality or a benign condition (14 true-positives, four true-negatives).</p>
         <p>There were three false-positives, a fat necrosis, a simple cyst and a normal breast; four indeterminates, a pale signal for a 14-mm complex cyst (C2), a 40-mm carcinoma (B5), a 16-mm malignancy (B5), and a 15-mm malignancy (C5); two false-negatives, a 15-mm malignancy (B5) and an 8-mm malignancy (R5, U5).</p>
         <p>The T scan demonstrated a sensitivity of 78% and a specificity of 57% excluding indeterminates. This study is ongoing.</p>
      </sec>
   </bdy>
</art>
