The accuracy of imprint cytology of breast core biopsy under ultrasound guidance

bcr469 BCJ Meeting abstract The accuracy of imprint cytology of breast core biopsy under ultrasound guidance Koshi S Goligher J Gottlieb M Bradley G Khan M Reyes R Walters TK

The Clinical Breast Unit, Queen Mary's Hospital, Sidcup, UK

Breast Cancer Res Symposium Mammographicum 2002 Meeting abstracts Symposium Mammographicum 2002 York, UK

17–19 July 2002

1465-5411 2002 4 Suppl 1 14 10.1186/bcr469 16 7 2002 2002 BioMed Central bcr-4-s1-14

Introduction

Histological analysis of core biopsy of breast lesions takes a minimum of 24 h, but imprint cytology of a core biopsy can be reported within an hour. This study validates the accuracy of imprint cytology from core biopsy of breast lesions obtained under ultrasound control.

Method

One hundred and fifty consecutive core biopsies from breast lesions of 142 patients were performed. The cores were placed on six microscopy slides to obtain imprint cytology. Imprint cytology and routine histology of the cores were assessed independently by two pathologists.

Results

See Table 1.

Table 1

Imprints

Cores

Inadequate

Benign

Atypical

Suspicious

Malignant

None of the imprints reported as malignant subsequently proved to be benign and only one of the imprints reported as benign subsequently proved to be malignant.

Conclusion

Imprint cytology of core biopsies correlates well with subsequent histological results and could be used to provide a rapid preliminary diagnosis. This rapidly available technique could reduce anxiety in patients with benign lesions and help treatment planning in patients with breast cancer.