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Overdiagnosis in breast cancer screening: the importance of length of observation period and lead time
Stephen W Duffy, Dharmishta Parmar Breast Cancer Research 2013, 15:R41 (16 May 2013)
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Illuminating luminal B: QSOX1 as a subtype-specific biomarker
Padmalaya Das, Gabrielle M Siegers, Lynne-Marie Postovit Breast Cancer Research 2013, 15:104 (15 May 2013)
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High mammographic density in women of Ashkenazi Jewish descent
Jennifer L Caswell, Karla Kerlikowske, John A Shepherd, Steven R Cummings, Donglei Hu, Scott Huntsman, Elad Ziv Breast Cancer Research 2013, 15:R40 (13 May 2013)
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The expression and significance of insulin-like growth factor-1 receptor and its pathway on breast cancer stem/progenitors
Wen-Wei Chang, Ruey-Jen Lin, John Yu, Wen-Ying Chang, Chiung-Hui Fu, Alan Chuan-Ying Lai, Jyh-Cherng Yu, Alice L Yu Breast Cancer Research 2013, 15:R39 (12 May 2013)
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Progesterone metabolites regulate induction, growth and suppression of estrogen- and progesterone receptor-negative human breast cell tumors
John P Wiebe, Guihua Zhang, Ian Welch, Heather-Anne T Cadieux-Pitre Breast Cancer Research 2013, 15:R38 (11 May 2013)
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Molecular apocrine breast cancers are aggressive estrogen receptor negative tumors overexpressing either HER2 or GCDFP15
Jacqueline Lehmann-Che, Anne Sophie Hamy, Raphael Porcher, Marc Barritault, Fatiha Bouhidel, Hanadi Habuellelah, Solenne Leman-Detours, Anne de Roquancourt, Laurence Cahen-Doidy, Edwige Bourstyn, Patricia de Cremoux, Cedric de Bazelaire, Marcela Albiter, Sylvie Giacchetti, Caroline Cuvier, Anne Janin, Marc Espie, Hugues de The, Philippe Bertheau Breast Cancer Research 2013, 15:R37 (11 May 2013)
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Editor’s summary
A novel and simplified molecular and immunohistochemical signature has been described for molecular apocrine breast tumours which could help with easy identification in clinical practice.
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Delivery of gene silencing agents for breast cancer therapy
Haifa Shen, Vivek Mittal, Mauro Ferrari, Jenny Chang Breast Cancer Research 2013, 15:205 (8 May 2013)
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Pregnancy protection of breast cancer: new insights reveal unanswered questions
Daniel Medina Breast Cancer Research 2013, 15:103 (8 May 2013)
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Parity induces differentiation and reduces Wnt/Notch signaling ratio and proliferation potential of basal stem/progenitor cells isolated from mouse mammary epithelium
Fabienne Meier-Abt, Emanuela Milani, Tim Roloff, Heike Brinkhaus, Stephan Duss, Dominique S Meyer, Ina Klebba, Piotr J Balwierz, Erik van Nimwegen, Mohamed Bentires-Alj Breast Cancer Research 2013, 15:R36 (29 April 2013)
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Editor’s summary
Early parity in mice alters the genomic signature of a distinct subset of mammary epithelial cells by inducing differentiation and reducing proliferation, ultimately protecting against breast cancer.
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Microwave imaging for neoadjuvant chemotherapy monitoring: initial clinical experience
Paul M Meaney, Peter A Kaufman, Lori S Muffly, Michael Click, Stephen P Poplack, Wendy A Wells, Gary N Schwartz, Roberta M di Florio-Alexander, Tor D Tosteson, Zhongze Li, Shireen D Geimer, Margaret W Fanning, Tian Zhou, Neil R Epstein, Keith D Paulsen Breast Cancer Research 2013, 15:R35 (24 April 2013)
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Editor’s summary
Microwave imaging may provide a low cost alternative to magnetic resonance and positron emission tomography for monitoring patient response to neoadjuvant chemotherapy (NCT).
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The estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarker
Michael L Salmans, Fang Zhao, Bogi Andersen Breast Cancer Research 2013, 15:204 (24 April 2013)
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Activating mutations and senescence secretome: new insights into HER2 activation, drug sensitivity and metastatic progression
Swarnali Acharyya Breast Cancer Research 2013, 15:309 (23 April 2013)
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Relationship of serum estrogens and estrogen metabolites to postmenopausal breast cancer risk: a nested case-control study
Roni T Falk, Louise A Brinton, Joanne F Dorgan, Barbara J Fuhrman, Timothy D Veenstra, Xia Xu, Gretchen L Gierach Breast Cancer Research 2013, 15:R34 (22 April 2013)
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miRNA expression profiling of 51 human breast cancer cell lines reveals subtype and driver mutation-specific miRNAs
Muhammad Riaz, Marijn TM van Jaarsveld, Antoinette Hollestelle, Wendy JC Prager-van der Smissen, Anouk AJ Heine, Antonius WM Boersma, Jingjing Liu, Jean Helmijr, Bahar Ozturk, Marcel Smid, Erik A Wiemer, John A Foekens, John WM Martens Breast Cancer Research 2013, 15:R33 (19 April 2013)
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Arthritis augments breast cancer metastasis: role of mast cells and SCF/c-Kit signaling
Lopamudra Roy, Jennifer M Curry, Mahnaz Sahraei, Dahlia M Besmer, Amritha Kidiyoor, Helen E Gruber, Pinku Mukherjee Breast Cancer Research 2013, 15:R32 (11 April 2013)
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Editor’s summary
A mouse model of rheumatoid arthritis shows that SCF/c-Kit signalling mast cells accumulate in bone and lung metastatic niches, which enhances breast cancer metastasis.
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Is TIMP-1 immunoreactivity alone or in combination with other markers a predictor of benefit from anthracyclines in the BR9601 adjuvant breast cancer chemotherapy trial?
Alison F Munro, Annette Bartels, Eva Balslev, Christopher J Twelves, David A Cameron, Nils Brünner, John MS Bartlett Breast Cancer Research 2013, 15:R31 (9 April 2013)
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HIF-1α stimulates aromatase expression driven by prostaglandin E2 in breast adipose stroma
Nirukshi U Samarajeewa, Fangyuan Yang, Maria M Docanto, Minako Sakurai, Keely M McNamara, Hironobu Sasano, Stephen B Fox, Evan R Simpson, Kristy A Brown Breast Cancer Research 2013, 15:R30 (8 April 2013)
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A randomised controlled phase II trial of pre-operative celecoxib treatment reveals anti-tumour transcriptional response in primary breast cancer
Rita D Brandão, Jürgen Veeck, Koen K Van de Vijver, Patrick Lindsey, Bart de Vries, Catharina HMJ van Elssen, Marinus J Blok, Kristien Keymeulen, Torik Ayoubi, Hubert JM Smeets, Vivianne C Tjan-Heijnen, Pierre S Hupperets Breast Cancer Research 2013, 15:R29 (8 April 2013)
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Editor’s summary
A randomized controlled trial finds that celecoxib, a COX-2 inhibitor, induces anti-tumor transcriptional changes in primary breast cancer tissue, suggesting a use for celecoxib in future treatments.
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Closing escape routes: inhibition of IL-8 signaling enhances the anti-tumor efficacy of PI3K inhibitors
Ashish Juvekar, Gerburg M Wulf Breast Cancer Research 2013, 15:308 (8 April 2013)
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Expression of quiescin sulfhydryl oxidase 1 is associated with a highly invasive phenotype and correlates with a poor prognosis in Luminal B breast cancer
Benjamin A Katchman, I Tolgay Ocal, Heather E Cunliffe, Yu-Hui Chang, Galen Hostetter, Aprill Watanabe, Janine LoBello, Douglas F Lake Breast Cancer Research 2013, 15:R28 (28 March 2013)
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The Hedgehog signalling pathway in breast development, carcinogenesis and cancer therapy
Mun Hui, Aurélie Cazet, Radhika Nair, D Watkins, Sandra A O'Toole, Alexander Swarbrick Breast Cancer Research 2013, 15:203 (28 March 2013)
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Elf5 - breast cancer's little helper
Hayley T Frend, Christine J Watson Breast Cancer Research 2013, 15:307 (27 March 2013)
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Risk of breast cancer in Lynch syndrome: a systematic review
Aung Win, Noralane M Lindor, Mark A Jenkins Breast Cancer Research 2013, 15:R27 (19 March 2013)
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Vaccinia virus GLV-1h153 is a novel agent for detection and effective local control of positive surgical margins for breast cancer
Sepideh Gholami, Chun-Hao Chen, Laurence J Belin, Emil Lou, Sho Fujisawa, Caroline Antonacci, Amanda Carew, Nanhai G Chen, Marina De Brot, Pat B Zanzonico, Aladar A Szalay, Yuman Fong Breast Cancer Research 2013, 15:R26 (18 March 2013)
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Editor’s summary
Oncolytic vaccinia virus, GLV1h-153, engineered to express the human sodium iodide symporter (hNIS) gene is useful in imaging cancers and can be used to identify and treat positive surgical margins of breast cancer in mice.
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Embryonic mammary signature subsets are activated in Brca1-/- and basal-like breast cancers
Marketa Zvelebil, Erik Oliemuller, Qiong Gao, Olivia Wansbury, Alan Mackay, Howard Kendrick, Matthew J Smalley, Jorge S Reis-Filho, Beatrice A Howard Breast Cancer Research 2013, 15:R25 (18 March 2013)
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