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1:

NHERF1: molecular brake on the PI3K pathway in breast cancer.

Georgescu MM.

Breast Cancer Res. 2008;10(2):106. Epub 2008 Apr 18.

PMID: 18430260 [PubMed - indexed for MEDLINE]

2:

Na+/H+ exchanger regulatory factor 1 inhibits platelet-derived growth factor signaling in breast cancer cells.

Pan Y, Weinman EJ, Dai JL.

Breast Cancer Res. 2008;10(1):R5. Epub 2008 Jan 11.

PMID: 18190691 [PubMed - indexed for MEDLINE]

3:

PTEN tumor suppressor associates with NHERF proteins to attenuate PDGF receptor signaling.

Takahashi Y, Morales FC, Kreimann EL, Georgescu MM.

EMBO J. 2006 Feb 22;25(4):910-20. Epub 2006 Feb 2.

PMID: 16456542 [PubMed - indexed for MEDLINE]

4:

NHERF1/EBP50 head-to-tail intramolecular interaction masks association with PDZ domain ligands.

Morales FC, Takahashi Y, Momin S, Adams H, Chen X, Georgescu MM.

Mol Cell Biol. 2007 Apr;27(7):2527-37. Epub 2007 Jan 22.

PMID: 17242191 [PubMed - indexed for MEDLINE]

5:

Roles of NHERF1/EBP50 in cancer.

Georgescu MM, Morales FC, Molina JR, Hayashi Y.

Curr Mol Med. 2008 Sep;8(6):459-68. Review.

PMID: 18781953 [PubMed - indexed for MEDLINE]

6:

The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells.

Cardone RA, Bellizzi A, Busco G, Weinman EJ, Dell'Aquila ME, Casavola V, Azzariti A, Mangia A, Paradiso A, Reshkin SJ.

Mol Biol Cell. 2007 May;18(5):1768-80. Epub 2007 Mar 1.

PMID: 17332506 [PubMed - indexed for MEDLINE]

7:

Na+-H+ exchanger regulatory factor 1 is a PDZ scaffold for the astroglial glutamate transporter GLAST.

Lee A, Rayfield A, Hryciw DH, Ma TA, Wang D, Pow D, Broer S, Yun C, Poronnik P.

Glia. 2007 Jan 15;55(2):119-29.

PMID: 17048262 [PubMed - indexed for MEDLINE]

8:

Suppression of breast cancer cell growth by Na+/H+ exchanger regulatory factor 1 (NHERF1).

Pan Y, Wang L, Dai JL.

Breast Cancer Res. 2006;8(6):R63.

PMID: 17078868 [PubMed - indexed for MEDLINE]

9:

Reduced PTEN expression in breast cancer cells confers susceptibility to inhibitors of the PI3 kinase/Akt pathway.

DeGraffenried LA, Fulcher L, Friedrichs WE, Grünwald V, Ray RB, Hidalgo M.

Ann Oncol. 2004 Oct;15(10):1510-6.

PMID: 15367412 [PubMed - indexed for MEDLINE]

10:

The phosphatidyl inositol 3-kinase signaling network: implications for human breast cancer.

Dillon RL, White DE, Muller WJ.

Oncogene. 2007 Feb 26;26(9):1338-45. Review.

PMID: 17322919 [PubMed - indexed for MEDLINE]

11:

The enteropathogenic Escherichia coli type III secretion system effector Map binds EBP50/NHERF1: implication for cell signalling and diarrhoea.

Simpson N, Shaw R, Crepin VF, Mundy R, FitzGerald AJ, Cummings N, Straatman-Iwanowska A, Connerton I, Knutton S, Frankel G.

Mol Microbiol. 2006 Apr;60(2):349-63.

PMID: 16573685 [PubMed - indexed for MEDLINE]

12:

Expression and clinicopathological significance of oestrogen-responsive ezrin-radixin-moesin-binding phosphoprotein 50 in breast cancer.

Song J, Bai J, Yang W, Gabrielson EW, Chan DW, Zhang Z.

Histopathology. 2007 Jul;51(1):40-53.

PMID: 17593079 [PubMed - indexed for MEDLINE]

13:

Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family.

Reczek D, Berryman M, Bretscher A.

J Cell Biol. 1997 Oct 6;139(1):169-79.

PMID: 9314537 [PubMed - indexed for MEDLINE]

14:

Roles of the RAF/MEK/ERK and PI3K/PTEN/AKT pathways in malignant transformation and drug resistance.

McCubrey JA, Steelman LS, Abrams SL, Lee JT, Chang F, Bertrand FE, Navolanic PM, Terrian DM, Franklin RA, D'Assoro AB, Salisbury JL, Mazzarino MC, Stivala F, Libra M.

Adv Enzyme Regul. 2006;46:249-79. Epub 2006 Jul 18.

PMID: 16854453 [PubMed - indexed for MEDLINE]

15:

Cortical stabilization of beta-catenin contributes to NHERF1/EBP50 tumor suppressor function.

Kreimann EL, Morales FC, de Orbeta-Cruz J, Takahashi Y, Adams H, Liu TJ, McCrea PD, Georgescu MM.

Oncogene. 2007 Aug 9;26(36):5290-9. Epub 2007 Feb 26.

PMID: 17325659 [PubMed - indexed for MEDLINE]

16:

Role of the scaffold protein RACK1 in apical expression of CFTR.

Auerbach M, Liedtke CM.

Am J Physiol Cell Physiol. 2007 Jul;293(1):C294-304. Epub 2007 Apr 4.

PMID: 17409124 [PubMed - indexed for MEDLINE]

18:

PTEN suppresses breast cancer cell growth by phosphatase activity-dependent G1 arrest followed by cell death.

Weng LP, Smith WM, Dahia PL, Ziebold U, Gil E, Lees JA, Eng C.

Cancer Res. 1999 Nov 15;59(22):5808-14.

PMID: 10582703 [PubMed - indexed for MEDLINE]

19:

PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model.

Weng LP, Smith WM, Brown JL, Eng C.

Hum Mol Genet. 2001 Mar 15;10(6):605-16.

PMID: 11230180 [PubMed - indexed for MEDLINE]

20:

Molecular aspects of gefitinib antiproliferative and pro-apoptotic effects in PTEN-positive and PTEN-negative prostate cancer cell lines.

Festuccia C, Muzi P, Millimaggi D, Biordi L, Gravina GL, Speca S, Angelucci A, Dolo V, Vicentini C, Bologna M.

Endocr Relat Cancer. 2005 Dec;12(4):983-98.

PMID: 16322337 [PubMed - indexed for MEDLINE]

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