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1:

Activated Akt1 accelerates MMTV-c-ErbB2 mammary tumourigenesis in mice without activation of ErbB3.

Young CD, Nolte EC, Lewis A, Serkova NJ, Anderson SM.

Breast Cancer Res. 2008;10(4):R70. Epub 2008 Aug 13.

PMID: 18700973 [PubMed - in process]

2:

Functional interaction between mouse erbB3 and wild-type rat c-neu in transgenic mouse mammary tumor cells.

Kim A, Liu B, Ordonez-Ercan D, Alvarez KM, Jones LD, McKimmey C, Edgerton SM, Yang X, Thor AD.

Breast Cancer Res. 2005;7(5):R708-18. Epub 2005 Jul 6.

PMID: 16168116 [PubMed - indexed for MEDLINE]

3:

Heregulin beta1 drives gefitinib-resistant growth and invasion in tamoxifen-resistant MCF-7 breast cancer cells.

Hutcheson IR, Knowlden JM, Hiscox SE, Barrow D, Gee JM, Robertson JF, Ellis IO, Nicholson RI.

Breast Cancer Res. 2007;9(4):R50.

PMID: 17686159 [PubMed - indexed for MEDLINE]

4:

Activation of erbB2 and c-src in phorbol ester-treated mouse epidermis: possible role in mouse skin tumor promotion.

Xian W, Rosenberg MP, DiGiovanni J.

Oncogene. 1997 Mar 27;14(12):1435-44.

PMID: 9136987 [PubMed - indexed for MEDLINE]

6:

c-Src modulates ErbB2 and ErbB3 heterocomplex formation and function.

Ishizawar RC, Miyake T, Parsons SJ.

Oncogene. 2007 May 24;26(24):3503-10. Epub 2006 Dec 18.

PMID: 17173075 [PubMed - indexed for MEDLINE]

7:

Compensatory ErbB3/c-Src signaling enhances carcinoma cell survival to ionizing radiation.

Contessa JN, Abell A, Mikkelsen RB, Valerie K, Schmidt-Ullrich RK.

Breast Cancer Res Treat. 2006 Jan;95(1):17-27.

PMID: 16267617 [PubMed - indexed for MEDLINE]

8:

Activation of ErbB3, EGFR and Erk is essential for growth of human breast cancer cell lines with acquired resistance to fulvestrant.

Frogne T, Benjaminsen RV, Sonne-Hansen K, Sorensen BS, Nexo E, Laenkholm AV, Rasmussen LM, Riese DJ 2nd, de Cremoux P, Stenvang J, Lykkesfeldt AE.

Breast Cancer Res Treat. 2008 Apr 14. [Epub ahead of print]

PMID: 18409071 [PubMed - as supplied by publisher]

9:

Sustained trophism of the mammary gland is sufficient to accelerate and synchronize development of ErbB2/Neu-induced tumors.

Landis MD, Seachrist DD, Abdul-Karim FW, Keri RA.

Oncogene. 2006 Jun 1;25(23):3325-34. Epub 2006 Jan 23.

PMID: 16434967 [PubMed - indexed for MEDLINE]

10:

Co-localization of multiple ErbB receptors in stratified epithelium of oral squamous cell carcinoma.

Bei R, Pompa G, Vitolo D, Moriconi E, Ciocci L, Quaranta M, Frati L, Kraus MH, Muraro R.

J Pathol. 2001 Oct;195(3):343-8.

PMID: 11673832 [PubMed - indexed for MEDLINE]

11:

Downregulation of erbB3 abrogates erbB2-mediated tamoxifen resistance in breast cancer cells.

Liu B, Ordonez-Ercan D, Fan Z, Edgerton SM, Yang X, Thor AD.

Int J Cancer. 2007 May 1;120(9):1874-82.

PMID: 17266042 [PubMed - indexed for MEDLINE]

12:

Investigation of the prognostic value of coexpressed erbB family members for the survival of colorectal cancer patients after curative surgery.

Lee JC, Wang ST, Chow NH, Yang HB.

Eur J Cancer. 2002 May;38(8):1065-71.

PMID: 12008194 [PubMed - indexed for MEDLINE]

13:

Transactivation of EGF receptor and ErbB2 protects intestinal epithelial cells from TNF-induced apoptosis.

Yamaoka T, Yan F, Cao H, Hobbs SS, Dise RS, Tong W, Polk DB.

Proc Natl Acad Sci U S A. 2008 Aug 19;105(33):11772-7. Epub 2008 Aug 13.

PMID: 18701712 [PubMed - indexed for MEDLINE]

14:

Transgenic mice with mammary gland targeted expression of human cortactin do not develop (pre-malignant) breast tumors: studies in MMTV-cortactin and MMTV-cortactin/-cyclin D1 bitransgenic mice.

van Rossum AG, van Bragt MP, Schuuring-Scholtes E, van der Ploeg JC, van Krieken JH, Kluin PM, Schuuring E.

BMC Cancer. 2006 Mar 14;6:58.

PMID: 16536875 [PubMed - indexed for MEDLINE]

15:

Neuregulin-1 only induces trans-phosphorylation between ErbB receptor heterodimer partners.

Li Z, Mei Y, Liu X, Zhou M.

Cell Signal. 2007 Mar;19(3):466-71. Epub 2006 Sep 15.

PMID: 16978839 [PubMed - indexed for MEDLINE]

16:

Development of leiomyosarcoma of the uterus in MMTV-CR-1 transgenic mice.

Strizzi L, Bianco C, Hirota M, Watanabe K, Mancino M, Hamada S, Raafat A, Lawson S, Ebert AD, D'Antonio A, Losito S, Normanno N, Salomon DS.

J Pathol. 2007 Jan;211(1):36-44.

PMID: 17072826 [PubMed - indexed for MEDLINE]

17:

Targeting ErbB2 and ErbB3 with a bispecific single-chain Fv enhances targeting selectivity and induces a therapeutic effect in vitro.

Robinson MK, Hodge KM, Horak E, Sundberg AL, Russeva M, Shaller CC, von Mehren M, Shchaveleva I, Simmons HH, Marks JD, Adams GP.

Br J Cancer. 2008 Nov 4;99(9):1415-25. Epub 2008 Oct 7.

PMID: 18841159 [PubMed - indexed for MEDLINE]

18:

The effect of estradiol on in vivo tumorigenesis is modulated by the human epidermal growth factor receptor 2/phosphatidylinositol 3-kinase/Akt1 pathway.

Lehnes K, Winder AD, Alfonso C, Kasid N, Simoneaux M, Summe H, Morgan E, Iann MC, Duncan J, Eagan M, Tavaluc R, Evans CH Jr, Russell R, Wang A, Hu F, Stoica A.

Endocrinology. 2007 Mar;148(3):1171-80. Epub 2006 Nov 30.

PMID: 17138652 [PubMed - indexed for MEDLINE]

19:

Trastuzumab therapy vs tetracycline controlled ERBB2 downregulation: influence on tumour development in an ERBB2-dependent mouse tumour model.

Hermes M, Schormann W, Brulport M, Uhlemann K, Lupatsch F, Horn LC, Schumann A, Allgaier C, Weishaupt M, Engeland K, Müller GA, Mössner J, Bauer A, Schiffer IB, Gebhard S, Schmidt M, Lausch E, Prawitt D, Wilhelm C, Hengstler JG.

Br J Cancer. 2008 May 6;98(9):1525-32. Epub 2008 Apr 29.

PMID: 18454161 [PubMed - indexed for MEDLINE]

20:

Evolution of somatic mutations in mammary tumors in transgenic mice is influenced by the inherited genotype.

Podsypanina K, Li Y, Varmus HE.

BMC Med. 2004 Jun 15;2:24.

PMID: 15198801 [PubMed - indexed for MEDLINE]

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